2-Isobutyl-3-methoxypyrazine, a potent bell-pepper odorant, binds to cow olfactory mucosa homogenate. The receptor is saturable in the micromolar range and is competitively inhibited by other bell-pepper odourants, but not by other pyrazines of different odours. Other tissues do not bind 2-isobutyl-3-methoxypyrazine at a significant extent. We suggest that this receptor is involved in odour discrimination.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1163633PMC
http://dx.doi.org/10.1042/bj2010245DOI Listing

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