European Spirometra forms corresponding to S. erinaceieuropaei in morphology, host specificity and periodical destrobilation were tested for a Sparganum Growth Factor (SGF "mansonoides") acting upon hypophysectomized male rats. A Polish form as well as Thai and Burmese forms did not show a SGF "mansonoides". The Polish form partially caused increased growth in normal laboratory mice (similar to a form from Thailand) and in Cricetulus griseus (SGF "non-mansonoides", restricted by host resistance). Procyon lotor can act both as paratenic and as definitive host for the Polish form. The Polish, Thai and Burmese forms are attributed to S. erinaceieuropaei. A Bulgarian form showed a typical SGF "mansonoides". 4 hyposectomized 100 g rats, each of which were implanted 5 spargana subcutaneously, showed weight gains up to 400 g within 7 to 8 weeks. Therefore, this Bulgarian form is treated provisionally as Spirometra sp.

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European Spirometra forms corresponding to S. erinaceieuropaei in morphology, host specificity and periodical destrobilation were tested for a Sparganum Growth Factor (SGF "mansonoides") acting upon hypophysectomized male rats. A Polish form as well as Thai and Burmese forms did not show a SGF "mansonoides".

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The plerocercoids of all Spirometra forms investigated up to now in this regard produce a "Sparganum Growth Factor" (SGF), i.e. one (or more) substance(s) with growth hormone-like effect on certain rodents.

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The effects of bovine growth hormone(GH) and Spirometra growth factor (SGF) on the in vivo concentrationions of glycolytic and citricacid (TCA) cycle intermediates in rat liver were investigated. The effects of these agents on the mitochondrial and cytoplasmic redox states, liver phosphorylation states, and adenylate kinase activity were also evaluated. The effects of SGF were studied in both normal and hypophysectomized rats,wheras GH effects ere examined only in hypophysectomized rats.

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