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http://dx.doi.org/10.1136/vr.110.14.343-a | DOI Listing |
Kaohsiung J Med Sci
January 2025
Department of Psychiatry, School of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan.
Attention-deficit/hyperactivity disorder (ADHD) is a common psychiatric condition among children and adolescents, often associated with a high risk of psychiatric comorbidities. Currently, ADHD diagnosis relies exclusively on clinical presentation and patient history, underscoring the need for clinically relevant, reliable, and objective biomarkers. Such biomarkers may enable earlier diagnosis and lead to improved treatment outcomes.
View Article and Find Full Text PDFFree Radic Res
January 2025
Radiation Biology & Health Sciences Division, Bio-science Group, Bhabha Atomic Research Centre, Trombay, Mumbai-400085, India.
Free radicals have been implicated in the pathogenesis of cancer along with cardiovascular, neurodegenerative, pulmonary and inflammatory disorders. Further, the relationship between oxidative stress and disease is distinctively established. Clinical trials using anti-oxidants for the prevention of disease progression have indicated some beneficial effects.
View Article and Find Full Text PDFIBRO Neurosci Rep
June 2025
Department of Human Anatomy and Medical Physiology, Faculty of Health Sciences, University of Nairobi, P.O. Box 30197- 00100, Nairobi, Kenya.
Khat ( Forsk), the natural source of cathinone and other psychoactive agents, is chewed by millions of persons in eastern Africa and the Arabian Peninsula for its psychostimulant effect. Using the conditioned place preference paradigm, this study tested fresh khat extract for place preference induction, extinction, and reinstatement. Female mice treated with 100 and 250 mg/kg of khat extract showed conditioned place preference, which was extinguished following a 16-day khat-free period.
View Article and Find Full Text PDFCureus
December 2024
Graduate Medical Education, Upstate University Hospital, Syracuse, USA.
Burnout among medical residents and fellows (postgraduate trainees) has been receiving significant attention in the scientific literature with far less focus on the factors that correlate with job satisfaction and well-being. A better understanding of the characteristics that increase job satisfaction (rather than just those that lead to burnout) may allow programs to develop and enhance those positive features, conceivably leading to improved mental health, retention, and recruitment. We hypothesize that job satisfaction among postgraduate trainees is positively impacted by feeling that their work is meaningful, that their work schedules are equitable, and that they are appreciated by their faculty.
View Article and Find Full Text PDFCureus
December 2024
General Surgery, Rajendra Institute of Medical Sciences, Ranchi, IND.
Phyllodes tumor is a type of fibroepithelial neoplasm involving the breast. This tumor is rarely reported in adolescents and the elderly and has a peak incidence in middle-aged women. Histologically, phyllodes tumors are classified as benign, borderline, or malignant.
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