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Thrips dynamics in Allium crops: Unraveling the role of reproductive mode and weather variables in Thrips tabaci population development.
PLoS One
January 2025
Plant Breeding, Wageningen University and Research, Wageningen, The Netherlands.
Thrips tabaci is the main thrips species affecting onion and related species. It is a cryptic species complex comprising three phylogenetic groups characterized by different reproductive modes (thelytoky or arrhenotoky) and host plant specialization. Thrips tabaci populations vary widely in genetic diversity, raising questions about the factor(s) that drive this diversity.
View Article and Find Full Text PDFThe Potential Role of Sanguinarine as an Inhibitor of Leishmania PP2C in the Induction of Apoptosis.
Acta Parasitol
January 2025
División de Investigación, Facultad de Medicina, Unidad de Investigación UNAM-INC, Universidad Nacional Autónoma de México, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano No. 1, Col. Sección XVI, Ciudad de México, C.P. 14080, México.
Leishmania spp. cause a wide range of human diseases, localized skin lesions, mucocutaneous and visceral infections. In the present study, the aim was to investigate the potential role of sanguinarine as a specific inhibitor of Leishmania PP2C that can induce apoptosis in the parasite.
View Article and Find Full Text PDFThe Global Secondary Metabolite Regulator Modulates Virulence, Ochratoxin Biosynthesis, and the Mode of Action of Biopesticides and Essential Oils.
Toxins (Basel)
December 2024
Laboratory of Plant Pathology, Department of Crop Science, Agricultural University of Athens, 118 55 Athens, Greece.
is considered one of the main fungi responsible for black and sour rot in grapes, as well as the production of the carcinogenic mycotoxin ochratoxin A. The global regulatory methyltransferase protein controls the production of various secondary metabolites in species, as well as influences sexual and asexual reproduction and morphology. The goal of this study was to investigate the role of the regulatory gene in physiology, virulence, and ochratoxin A (OTA) production by deleting this gene from the genome of a wild-type strain.
View Article and Find Full Text PDFFungal Biocontrol Agents in the Management of Postharvest Losses of Fresh Produce-A Comprehensive Review.
J Fungi (Basel)
January 2025
Gastro-Intestinal Microbiology and Biotechnology Unit, Agricultural Research Council-Animal Production, Private Bag X02, Irene, Pretoria 0062, South Africa.
Postharvest decay of vegetables and fruits presents a significant threat confronting sustainable food production worldwide, and in the recent times, applying synthetic fungicides has become the most popular technique of managing postharvest losses. However, there are concerns and reported proofs of hazardous impacts on consumers' health and the environment, traceable to the application of chemical treatments as preservatives on fresh produce. Physical methods, on the other hand, cause damage to fresh produce, exposing it to even more infections.
View Article and Find Full Text PDFExploiting Cancer Dormancy Signaling Mechanisms in Epithelial Ovarian Cancer Through Spheroid and Organoid Analysis.
Cells
January 2025
The Mary and John Knight Translational Ovarian Cancer Research Unit, Verspeeten Family Cancer Centre, London, ON N6A 5W9, Canada.
Epithelial ovarian cancer (EOC) exhibits a unique mode of metastasis, involving spheroid formation in the peritoneum. Our research on EOC spheroid cell biology has provided valuable insights into the signaling plasticity associated with metastasis. We speculate that EOC cells modify their biology between tumour and spheroid states during cancer dormancy, although the specific mechanisms underlying this transition remain unknown.
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