The clinical efficacy of short-term therapy was investigated in a prospective study of 100 patients with urinary tract infection following gynecologic surgery. Nitrofurantoin macrocrystals were administered to 50 patients in a dosage of 100 mg every 12 hours for two days, trimethoprim/sulfamethoxazole was administered also to 50 patients in a dosage of 160 and 800 mg respectively every 12 hours for two days. The cure rate for nitrofurantoin macrocrystals was 76%, that for TMP/SMX 86%. The differences between the cure rates of the two antimicrobials and the cure rates of the 2-days treatment and the 7-days treatment used previously were not significant (p greater than 0,1).
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