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Introduction: The etiology of generalized anxiety disorder (GAD) has not been fully understood, and oxidative stress may potentially contribute to its pathogenesis. However, there is no published evidence concerning the possible influence of oxidative stress on antidepressant treatment outcomes. This study investigated the ability of oxidative stress markers to predict treatment outcomes in GAD patients treated with selective serotonin reuptake inhibitors (SSRIs).
View Article and Find Full Text PDFDiscordance analyses comparing LDL cholesterol, Non-HDL cholesterol, and apolipoprotein B for cardiovascular risk estimation.
Atherosclerosis
February 2025
Department of Clinical Biochemistry, Copenhagen University Hospital - Herlev Gentofte, Denmark; The Copenhagen General Population Study, Copenhagen University Hospital - Herlev Gentofte, Denmark; The Copenhagen City Heart Study, Copenhagen University Hospital - Bispebjerg Frederiksberg, Denmark; Institute of Clinical Medicine, Faculty of Health and Medical Science, University of Copenhagen, Denmark. Electronic address:
For decades, studies have tried to identify the cholesterol marker that best reflects risk of atherosclerotic cardiovascular disease(ASCVD). Comparing low-density-lipoprotein(LDL) cholesterol, non-high-density-lipoprotein(non-HDL) cholesterol, and apolipoprotein B(apoB) as ASCVD risk markers has been challenged by high correlation between them. Thus, discordance analyses, directly addressing disagreements between the cholesterol markers, have emerged.
View Article and Find Full Text PDFPredictive Value of Monocyte to High-Density Lipoprotein Cholesterol Ratio for Target Lesion Revascularization in Patients With Drug-Eluting Stent Implantation.
Int J Gen Med
March 2025
Department of Cardiology, Tianjin Chest Hospital, Tianjin, People's Republic of China.
Background: Severe in-stent restenosis (ISR) following the implantation of drug-eluting stent (DES) can lead to recurrent angina pectoris or even acute myocardial infarction, thereby necessitating target lesion revascularization (TLR). Prior studies have confirmed the correlation between the monocyte to high-density lipoprotein cholesterol ratio (MHR) and ISR after DES implantation. The potential of MHR to predict TLR following DES implantation remains an area of ongoing research and may have significant clinical implications.
View Article and Find Full Text PDFPrevalence and Correlates of Osteoporosis and Metabolic Syndrome Among Patients With Chronic Obstructive Pulmonary Disease at a Rural Tertiary Healthcare Center in India.
Cureus
February 2025
Department of Respiratory Medicine, Uttar Pradesh University of Medical Sciences, Etawah, IND.
Background Chronic obstructive pulmonary disease (COPD) results from chronic inflammation triggered by various risk factors. This inflammation can also impact other organ systems. COPD patients often have comorbidities such as osteoporosis and metabolic syndrome.
View Article and Find Full Text PDFExploring the Intersections between Triglyceride-rich Lipoproteins and Acute Coronary Syndrome: A Cross-sectional Study.
Ann Afr Med
March 2025
Department of General Medicine, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pimpri, Pune, Maharashtra, India.
Background: Within 20 years, cardiovascular disease (CVD), which is currently the main cause of death in the Indian subcontinent, is expected to overtake all other causes of death in South Asia. Acute coronary syndrome (ACS), a critical form of CVD, is associated with multiple risk factors including hyperlipidemia. While triglyceride-rich lipoproteins (TRLs) and their remnants are well-studied traditional markers such as low-density lipoprotein (LDL-C) and high-density lipoprotein-cholesterol (HDL-C), new research indicates that they may possibly be important in ACS risk.
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