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Investigating Cell-Induced Mixing Dynamics in Microfluidic Droplets Using the Lattice Boltzmann Method.
Langmuir
January 2025
CNNFM Lab, School of Mechanical Engineering, College of Engineering, University of Tehran, P.O. Box 11155-4563 Tehran, Iran.
This study investigates the impact of cell dynamics on mixing efficiency within a microfluidic droplet, emphasizing the relationship between cell motion, deformability, and resultant asymmetry in velocity and concentration fields. Simulations were conducted for droplets containing encapsulated cells at varying Peclet numbers ( = 100-800) and coupling constants ( = 0.0025, 0.
View Article and Find Full Text PDFAnalysis of radiation oncology integration within general practitioners' daily patient care: a cross-sectional survey in Germany.
Strahlenther Onkol
January 2025
Department of Radiation Oncology, Klinikum rechts der Isar, School of Medicine and Health, Technical, University of Munich (TUM), Ismaninger Str. 22, 81675, Munich, Germany.
Purpose: General practitioners (GPs) play a crucial role in providing interdisciplinary care for radiation oncology patients. This study aims to understand the specific needs and challenges faced by general practitioners in Germany when treating oncology patients.
Methods: A comprehensive web-based questionnaire with 24 items was disseminated to GPs in Germany via email using survio.
An 18-year comprehensive safety study on microfocused ultrasound and monopolar radiofrequency combined with cosmetic injectables in 1,040 patients.
Arch Dermatol Res
January 2025
Department of Dermatology, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Republic of Korea.
Microfocused ultrasound (MFU) and (MRF) are non-invasive modalities widely used for skin rejuvenation and are often combined with injectables, including neuromodulators and soft tissue fillers. However, large-scale, long-term safety data on such combination therapies are lacking. To address this gap, we conducted a retrospective chart review at two private practice dermatology clinics in South Korea from June 2005 to December 2023.
View Article and Find Full Text PDFRevered and Reviled: The Plight of the Vanishing Sea Cucumbers.
Ann Rev Mar Sci
January 2025
Sea Cucumber Specialist Group, Species Survival Commission, International Union for Conservation of Nature, Gland, Switzerland.
Sea cucumbers paradoxically suffer from being both highly prized and commonly disregarded. As an Asian medicine and delicacy, they command fabulous prices and are thus overfished, poached, and trafficked. As noncharismatic animals, many are understudied and inadequately protected.
View Article and Find Full Text PDFBile acid sequestrant inhibits gluconeogenesis via inducing hepatic cysteine dioxygenase type 1 to reduce cysteine availability.
Am J Physiol Gastrointest Liver Physiol
January 2025
Harold Hamm Diabetes Center, Department of Biochemistry and Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104.
Bile acid sequestrants such as cholestyramine (ChTM) are gut-restricted bile acid binding resins that block intestine bile acid absorption and attenuate hepatic bile acid signaling. Bile acid sequestrants induce hepatic bile acid synthesis to promote cholesterol catabolism and are cholesterol lowering drugs. Bile acid sequestrants also reduce blood glucose in clinical trials and are approved drugs for treating hyperglycemia in type-2 diabetes.
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