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Pneumatic Distension of Ventricular Mural Architecture Validated Histologically.
Rofo
November 2016
Institute of Genetic Medicine, Newcastle University, London, United Kingdom of Great Britain and Northern Ireland.
There are ongoing arguments as to how cardiomyocytes are aggregated together within the ventricular walls. We used pneumatic distension through the coronary arteries to exaggerate the gaps between the aggregated cardiomyocytes, analyzing the pattern revealed using computed tomography, and validating our findings by histology. We distended 10 porcine hearts, arresting 4 in diastole by infusion of cardioplegic solutions, and 4 in systole by injection of barium chloride.
View Article and Find Full Text PDFArrhythmias and hemodialysis: role of potassium and new diagnostic tools.
Ren Fail
May 2009
Department of Internal Medicine, University of Messina, Messina, Italy.
Cardiovascular diseases represent the main causes of death in patients affected by renal failure, and arrhythmias are frequently observed in patients undergoing hemodialysis. Dialytic treatment per se can be considered as an arrhythmogenic stimulus; moreover, uraemic patients are characterized by a "pro-arrhythmic substrate" because of the high prevalence of ischaemic heart disease, left ventricular hypertrophy and autonomic neuropathy. One of the most important pathogenetic element involved in the onset of intra-dialytic arrhythmias is the alteration in electrolytes concentration, particularly calcium and potassium.
View Article and Find Full Text PDFRespiration and postural sway: detection of phase synchronizations and interactions.
Hum Mov Sci
September 2004
Dipartimento di Elettronica Applicata, Università degli Studi Roma TRE, Via della Vasca Navale, 84, I-00146, Italy.
The aim of the central nervous system in upright stance is to control an intrinsically unstable plant. Internal disturbances, such as haemodynamics and respiration, constitute an endogenous threat to equilibrium. The way CNS reacts to those perturbations was studied in this work, through the analysis of summary scores taken from posturographic and pneumographic data.
View Article and Find Full Text PDFSleep-related breathing disorders following discharge from intensive care.
Intensive Care Med
April 2000
Department of Anaesthesia and Intensive Care, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom.
Objectives: To determine the incidence of sleep-related breathing disorders and nocturnal hypoxaemia in patients discharged from ICU following prolonged mechanical ventilation.
Design: Prospective, consecutive patient observational study.
Setting: The medical and surgical wards of a University Hospital.
Theophylline for infants with abnormal pneumographic results. A randomized double blind, placebo-controlled trial.
Klin Padiatr
June 1997
Intensive Care Unit, Gottfried von Preyer Children's Hospital, Vienna, Austria.
To evaluate the effectiveness of theophylline on density of central apnoeas and on incidence of periodic breathing; to compare the effect with age-related resolution of pneumogram abnormalities. Ninety-six infants (mean age 27.4 days; mean birth weight 2502 gm) with abnormal pneumographic results were randomly allocated to receive theophylline or placebo.
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