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Demographics and outcomes of acute type A aortic dissection in young adults in southeastern China: impact of syndromic heritable thoracic aortic disease.
Ann Med
December 2025
Department of Cardiovascular Surgery, Fujian Medical University Union Hospital, Fuzhou, PR China.
Background: This study aimed to investigate the demographics and to evaluate long-term outcomes of acute type A aortic dissection (ATAAD) in surgically treated patients ≤40 years in China.
Methods: This study included patients aged ≤40 with ATAAD who underwent surgical treatment at our institution between 2015 and 2019. The patients were categorized into groups according to heritable thoracic aortic disease (HTAD) presence or absence.
Unsupervised machine learning model for phenogroup-based stratification in acute type A aortic dissection to identify postoperative acute gastrointestinal injury.
Front Cardiovasc Med
January 2025
Department of Anesthesiology and Operation, The First Hospital of Lanzhou University, Lanzhou, Gansu, China.
Objective: We aimed to explore the application value of unsupervised machine learning in identifying acute gastrointestinal injury (AGI) after extracorporeal circulation for acute type A aortic dissection (ATAAD).
Methods: Patients who underwent extracorporeal circulation for ATAAD at the First Hospital of Lanzhou University from January 2016 to January 2021 were included. Unsupervised machine learning algorithm was used to stratify patients into different phenogroups according to the similarity of their clinical features and laboratory test results.
Downregulation of RhoA/ROCK1/YAP/F-actin causing decreased aortic smooth muscle cell stiffness promotes aortic dissection formation.
Life Metab
October 2024
Department of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Downregulated RhoA/ROCK1/YAP/F-actin axis leads to decreased AoSMC stiffness and promotes AD formation.
View Article and Find Full Text PDFDevelopment of a predictive nomogram for postoperative acute respiratory distress syndrome in Stanford type A aortic dissection patients: a retrospective study.
Rev Port Cardiol
January 2025
Department of Cardiovascular Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China. Electronic address:
Introduction And Objectives: This retrospective study aimed to develop a nomogram to predict the risk of postoperative acute respiratory distress syndrome (ARDS) in patients with Stanford type A acute aortic dissection.
Methods: The study included patients who underwent surgical repair for Stanford type A acute aortic dissection between January 2020 and December 2023. Demographic data, surgical details, intraoperative information, and postoperative outcomes were collected.
Developing predictive nomogram models using quantitative electroencephalography for brain function in type a aortic dissection: a prospective observational study.
Int J Surg
January 2025
Department of Cardio-Thoracic Surgery, Nanjing Drum Tower Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Nanjing, Jiangsu, China.
Background: Type A aortic dissection (TAAD) remains a significant challenge in cardiac surgery, presenting high risks of adverse outcomes such as permanent neurological dysfunction and mortality despite advances in medical technology and surgical techniques. This study investigates the use of quantitative electroencephalography (QEEG) to monitor and predict neurological outcomes during the perioperative period in TAAD patients.
Methods: This prospective observational study was conducted at the hospital, involving patients undergoing TAAD surgery from February 2022 to January 2023.
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