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A preliminary study of cell-based bone tissue engineering into 3D-printed β-tricalcium phosphate scaffolds and polydioxanone membranes.
Sci Rep
December 2024
Department of Basic Sciences, Araçatuba Dental School, São Paulo State University - UNESP, Araçatuba, 16066-840, Brazil.
Treatment of complex craniofacial deformities is still a challenge for medicine and dentistry because few approach therapies are available on the market that allow rehabilitation using 3D-printed medical devices. Thus, this study aims to create a scaffold with a morphology that simulates bone tissue, able to create a favorable environment for the development and differentiation of osteogenic cells. Moreover, its association with Plenum Guide, through cell-based tissue engineering (ASCs) for guided bone regeneration in critical rat calvarial defects.
View Article and Find Full Text PDFBiomaterials for bone tissue engineering: achievements to date and future directions.
Biomed Mater
December 2024
Engineered Biomedical Materials Research and Innovation Centre (EnBioMatRIC), Department of Mechanical Engineering, Manipal University Jaipur, Jaipur, Rajasthan, India.
Advancement in medicine and technology has resulted into prevention of countless deaths and increased life span. However, it is important to note that, the modern lifestyle has altered the food habits, witnessed increased life-style stresses and road accidents leading to several health complications and one of the primary victims is the bone health. More often than ever, healthcare professionals encounter cases of massive bone fracture, bone loss and generation of critical sized bone defects.
View Article and Find Full Text PDFStrontium-Doped Whitlockite Scaffolds for Enhanced Bone Regeneration.
ACS Appl Mater Interfaces
December 2024
School of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul 08826, Republic of Korea.
Bone graft substitutes to repair critical-sized bone fractures have experienced significant development over the last few decades. Among them, whitlockite (WH)-based bone grafts have proven to be effective in mediating bone healing. In the current study, a next generation, nature-inspired scaffold was developed with strontium-functionalized whitlockite nanoparticles (nSrWH) to enhance the intrinsic properties of WH.
View Article and Find Full Text PDFInfluence of minimally invasive cavities on color stability of dental crowns with different filling sealers.
Braz Oral Res
November 2024
Universidade de São Paulo - USP, School of Dentistry of Ribeirão Preto, Department of Restorative Dentistry, Ribeirão Preto, SP, Brazil.
Article Synopsis
- * Maxillary central incisors were used, with color changes measured before and after treatment, plus after a year of storage, revealing that color became more yellow over time.
- * Results indicated that neither the sealing method nor the access approach influenced tooth discoloration significantly, though more voids were noted with the Bio-C sealer when using minimally invasive access.
Personalized bioceramic grafts for craniomaxillofacial bone regeneration.
Int J Oral Sci
October 2024
Department of Cariology, Restorative Sciences and Endodontics, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
Article Synopsis
- * Additive manufacturing allows for the creation of customizable 3D biomaterial scaffolds that promote bone formation through guiding cell activities and can degrade as new bone tissue forms, making them suitable for use as synthetic grafts.
- * This review discusses advancements in bioceramic grafts created by 3D printing, including details on material properties, fabrication techniques, and the biological responses of these materials, while also summarizing their clinical applications and potential for personalized craniomaxillofacial bone
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