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Clozapine treatment of a Japanese patient during pregnancy: Effect on fetal heart rate.
Neuropsychopharmacol Rep
December 2024
Department of Psychiatry, Japanese Red Cross Narita Hospital, Narita-shi, Chiba, Japan.
Article Synopsis
- A case study of a 29-year-old Japanese woman with schizophrenia on clozapine during pregnancy showed no complications until a late incident of premature rupture of membranes, which led to an emergency cesarean section.
- The study indicates that clozapine and its metabolite norclozapine were transferred to the fetus and may have impacted fetal heart rate; it advises careful monitoring of clozapine levels and fetal health during pregnancy for better outcomes.
Severe Upper Lid Fornix Prolapse After a Ptosis Repair in Floppy Eyelid Syndrome: A Case Report.
Ann Plast Surg
November 2023
From the Elson S. Floyd College of Medicine, Washington State University.
Article Synopsis
- A 43-year-old woman with floppy eyelid syndrome (FES) presented with severe ptosis, causing difficulty in driving and chronic eye issues like tearing and crusting.
- She underwent surgical procedures, including a wedge excision and ptosis repair, which initially led to complications that obstructed her vision.
- After a fornix reconstruction, her symptoms improved, and this case highlights the need for further research on complications in younger patients with FES.
Adherence to continuous positive airway pressure for the treatment of obstructive sleep apnea in neurodegenerative diseases: A systematic review.
Sleep Med Rev
October 2023
Respiratory Epidemiology and Clinical Research Unit, Research Institute of the McGill University Health Centre - Montreal, Quebec, Canada; Respiratory Division & Sleep Laboratory, McGill University Health Centre - Montreal, Quebec, Canada.
Obstructive sleep apnea (OSA) is prevalent in patients with neurodegenerative diseases and is associated with worse outcomes. Positive airway pressure therapy has the potential to benefit these patients but can be challenging in this population. Our primary aim was to describe positive pressure therapy adherence.
View Article and Find Full Text PDFSafety of Alprazolam Use in Pregnancy in Western Australia: A Retrospective Cohort Study Using Linked Health Data.
J Psychoactive Drugs
October 2024
School of Population & Global Health, The University of Western Australia, Crawley, Western Australia, Australia.
The use of alprazolam in pregnancy can adversely affect maternal and neonatal health. This study examined neonatal outcomes following exposure to alprazolam in pregnancy. Women prescribed alprazolam during pregnancy ( = 48) between 2014 and 2018 were identified from routinely-collected state administrative prescribing records and perinatal data.
View Article and Find Full Text PDFInfection-Induced Rhabdomyolysis in a Pregnant Woman with Undiagnosed Myotonic Dystrophy: A Case Report.
Medicina (Kaunas)
April 2023
Department of Obstetrics and Gynecology, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu 41944, Republic of Korea.
A 34-year-old nulliparous gravid female presented with acute bilateral pyelonephritis at 29 + 5 weeks gestation. The patient was relatively well until two weeks ago when a slight increase in amniotic fluid was noted. Further investigation revealed myoglobinuria and significantly elevated levels of creatine phosphokinase.
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