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Design and fabrication of customized brain slice matrices using CAD and 3D printing technology.
PLoS One
January 2025
Department of Anatomy, Nihon University School of Dentistry, Tokyo, Japan.
This study presents a novel method for creating customized brain slice matrices using Computer-Aided Design (CAD) and 3D printing technology. Brain Slice Matrices are essential jigs for the reproducible preparation of brain tissue sections in neuroscience research. Our approach leverages the advantages of 3D printing, including design flexibility, cost-effectiveness, and rapid prototyping, to produce custom-made brain matrices based on specific morphometric measurements.
View Article and Find Full Text PDFEvaluation of radiation therapy on grafted and non-grafted defects: an experimental rat model.
J Appl Oral Sci
January 2025
Universidade Federal de Uberlândia, Faculdade de Odontologia, Departamento de Periodontia e Implantodontia, Uberlândia, Brasil.
Objective: This study aimed to assess the effects of a single-dose radiation therapy (15 Gy) on grafted and non-grafted defects, bone microarchitecture, and collagen maturity.
Methodology: Bone defects were surgically created in rat femurs. The right femur defect was filled with blood clot (group "Clot") and the left femur defect by deproteinized bovine bone mineral graft (group "Xenograft").
Association between circulating inflammatory proteins and temporomandibular disorders: insight from a two-sample Mendelian randomization analysis.
J Appl Oral Sci
January 2025
Shanghai Jiao Tong University School of Medicine, College of Stomatology, Shanghai Ninth People's Hospital, Department of Orthodontics, Shanghai, China.
Background: Past studies have indicated links between specific inflammatory proteins in the bloodstream and temporomandibular disorders (TMDs). Nonetheless, there remains the need for further solid research pinpointing the exact causes behind these associations. This Mendelian randomization (MR) study aims to examine the association between 91 circulating inflammatory proteins and TMDs.
View Article and Find Full Text PDFOsteoclastogenesis markers in craniofacial bone defects after demineralized dentin material membrane implantation as guided bone regeneration.
J Appl Oral Sci
January 2025
Universitas Airlangga, Faculty of Dental Medicine, Department of Oral Biology, Surabaya, East Java, Indonesia.
Unlabelled: Guided bone regeneration (GBR) is an alternative treatment for craniofacial bone defects reconstruction through membrane barrier adaptation, such as demineralized dentin material membrane (DDMM). DDMM is used as a substitute for GBR material, which aligns with Green Economy principles, it has a good biological osteoinductive and osteoconductive effects, and its structure resembles bones. The balance of bone remodeling when experiencing craniofacial defects will be altered and allow changes to resorption activity, so the mechanisms of osteoclastogenesis and bone resorption are vital.
View Article and Find Full Text PDFSleep recovery ameliorates submandibular salivary gland inflammation associated with paradoxical sleep deprivation in male Wistar rats.
J Appl Oral Sci
January 2025
University of Ibadan, College of Medicine, Department of Physiology, Ibadan, Nigeria.
Objective: Submandibular salivary gland inflammation has been suggested as one of the mechanisms underlying impaired salivary secretion associated with sleep deprivation (SD). However, whether the salivary inflammatory response occurs to the same extent in paradoxical sleep deprivation with or without sleep recovery remains unknown. This study evaluated the extent to which inflammation influences salivary impairments associated with paradoxical sleep deprivation with or without sleep recovery.
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