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Diminutive polyps: histopathology, spatial distribution, and clinical significance. | LitMetric

AI Article Synopsis

  • Nearly half of the 329 studied diminutive colon polyps were found to be neoplastic (49.2%), while a similar percentage were nonneoplastic (49.9%).
  • A significant portion of the polyps were metaplastic (36.8%), mostly located in the distal large bowel, particularly the rectosigmoid area (52.9%).
  • The results imply that many more diminutive polyps may be neoplastic and at risk for progressing to cancer than previously thought.

Article Abstract

This retrospective study of 329 diminutive colon polyps revealed that 49.2% of the polyps were neoplastic, whereas 49.9% were nonneoplastic. 36.8% of the polyps were metaplastic, and 0.9% had mixed metaplastic and adenomatous components. The metaplastic polyps had a predominance in the distal portion of the large bowel, with 76.9% being located distal from the splenic flexure and 52.9% being located in the rectosigmoid area. Neoplastic polyps were distributed throughout the colon, with 65.4% located from the splenic flexure distally and 34.5% located proximal to the splenic flexure. These findings suggest that a much larger proportion of diminutive polyps are neoplastic and therefore at risk to progress to carcinoma than previously considered.

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Source
http://dx.doi.org/10.1016/s0016-5107(82)72954-2DOI Listing

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