To help curb excessive radiography, we developed a protocol for selecting patients with injured extremities who need x-ray examination, and we tested the protocol prospectively in 848 patients to determine its safety and effectiveness. Strict adherence to the protocol would have reduced x-ray usage by 12 per cent for upper extremities and 19 per cent for lower extremities. The actual reductions were 5 per cent and 16 per cent, respectively, since further reductions were limited by patient's demands for x-ray examinations. One fracture in 287 were missed, but the treatment was appropriate and the outcome satisfactory. By eliminating superfluous x-ray procedures, the protocol could reduce charges by $79 million to $139 million nationwide, without compromising quality of care or increasing malpractice liability. Nevertheless, even the best protocol cannot eliminate all negative x-ray studies. These results should serve as a stimulus for judicious use of radiography, but also as a warning to avoid overzealous cost-containment strategies that would reduce x-ray usage to below a safe threshold.
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http://dx.doi.org/10.1056/NEJM198202113060604 | DOI Listing |
Facial Plast Surg Aesthet Med
January 2025
Division of Facial Plastic and Reconstructive Surgery, Stanford University School of Medicine, Stanford, California, USA.
To investigate the effectiveness of isotretinoin use in patients with thick nasal skin to improve rhinoplasty outcomes. The Population Intervention Comparison Outcome framework was utilized for selecting relevant studies for review. The databases of Medline, Embase, Cinahl, Central, Scopus, and Web of Science were searched in June 2024.
View Article and Find Full Text PDFRadiol Imaging Cancer
January 2025
From the Department of Radiology (A.C., A.N.Y., R.E., C.H., G.L., M.M., E.B.J., A.L.C., B.G., G.S.K., A.O.), Sanford J. Grossman Center of Excellence in Prostate Imaging and Image Guided Therapy (A.C., A.N.Y., M.M., A.L.C., B.G.), Department of Surgery, Section of Urology (G.G., L.F.R., P.K.M., S.E.), Department of Pathology (T.A.), and Department of Public Health Sciences (M.G.), University of Chicago, 5841 S Maryland Ave, MC 2026, Chicago, IL 60637.
Purpose To evaluate the use of an automated hybrid multidimensional MRI (HM-MRI)-based tool to prospectively identify prostate cancer targets before MRI/US fusion biopsy in comparison with Prostate Imaging and Reporting Data System (PI-RADS)-based multiparametric MRI (mpMRI) evaluation by expert radiologists. Materials and Methods In this prospective clinical trial (ClinicalTrials.gov registration no.
View Article and Find Full Text PDFJBRA Assist Reprod
January 2025
Molecular Medicine, Nutrigenomics and Public Health Research Laboratory, Department of Bio-Medical Laboratory Science and Management, Vidyasagar University, Midnapore 721 102, West Bengal, India.
Objective: The study focused the contraceptive efficacy of hydro-ethanolic (60:40) extract (HEE) of Caesalpinia pulcherrima leaves in human and rat sperm samples by in vitro study.
Methods: Six young fertile adult males were selected for semen collection. Sperm samples were collected from six adult rat also by chopping the epididymis along with the collection of testicles, epididymis, and liver.
Front Vet Sci
January 2025
Experimental Zooprophylactic Institute of Southern Italy, Portici, Naples, Italy.
Introduction: The decline of the European/western honeybee () population is on account of a plethora of microorganisms, such as and , two microsporidian fungi responsible of nosemosis that affects welfare and production of the bee industry. Accordingly, this study aimed to investigate the presence of both pathogens in bees, pollen and honey from apiaries in Southwestern Italy.
Methods: From March to July 2022 and 2023, apiaries ( = 10) were selected and classified as High Impact Areas (HIAs, = 5) and Low Impact Areas (LIAs, = 5) according to a 5-point environmental risk index based on factors affecting bee health sand related productions.
Campbell Syst Rev
March 2025
School of Basic Medical Sciences, Evidence-Based Medicine Centre Lanzhou University Lanzhou China.
Background: A systematic review is a type of literature review that uses rigorous methods to synthesize evidence from multiple studies on a specific topic. It is widely used in academia, including medical and social science research. Social science is an academic discipline that focuses on human behaviour and society.
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