Amyloidosis involving the upper portion of the respiratory tract is an uncommon disorder that may occur as an isolated phenomenon or, more unusually, as part of a systemic amyloidosis. This case of a 66-year-old man with amyloidosis of the larynx and trachea illustrates some recently developed concepts and techniques in the diagnosis and management of this problem.
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Ear Nose Throat J
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Weifang People's Hospital, Weifang, Shandong, China.
Article Synopsis
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The subglottic involvement is an independent risk factor for recurrence of laryngeal amyloidosis.
Eur Arch Otorhinolaryngol
November 2023
Department of Otolaryngology-Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiao Tong University, No. 157 Xi-Wu Road, Xi'an, 710004, Shannxi, China.
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Ear Nose Throat J
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Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
The purpose of this study is to evaluate clinical information, laboratory results, and pathologic findings of patients with amyloidosis involving larynx, oral cavity, and pharynx from our institute. A total of 39 specimens from 28 patients were retrieved from 2000 to 2020. Data collection included clinical presentation, radiographic, laboratory results, and pathologic findings.
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Semin Diagn Pathol
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Department of Pathology, E422 Doan Hall, 410W 10th Ave, Columbus, OH 43210, United States. Electronic address:
Small biopsies in the larynx can make a definitive diagnosis challenging due to the sampling or tangential sectioning. The differential diagnosis can be divided into mucosal lesions (squamous papillomas, intraepithelial dysplasia, and invasive squamous cell carcinoma) or submucosal lesions (vocal cord polyps/nodules, amyloidosis, granular cell tumor, rhabdomyoma, neuroendocrine neoplasms, salivary gland tumors, and cartilaginous tumors). Diagnostic criteria (both morphologic and immunohistochemical) are reviewed to arrive at a diagnosis even on small biopsy.
View Article and Find Full Text PDFFlexible Endoscopic Surgery for Benign Nonepithelial Lesions of the Larynx.
Indian J Otolaryngol Head Neck Surg
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Clinic of Otolaryngology, "N.Testemițanu" University of Medicine and Pharmacy, Chișinău, Republic of Moldova.
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