In examination of patients with thyrotoxicosis, aged from 14 to 24 years, there was revealed a reduction of the activity of the mediatory link of the sympathico-adrenal ssystem without any connection with age, the severity and duration of the disease, and also with the efficacy of drug therapy. The functional test with insulin in patients with thyrotoxicosis permitted to detect definite reserve possibilities of the adrenergic regulation intensified with increased duration of the disease and with advance of the patient's age, but not with increased severity of the disease. The insulin test offered a possibility of assessing the sympathico-adrenal system reactivity in cases of different degree of the disease compensation.
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