Relaxation training tapes vary in voice gender and background, but little has been published regarding the preferences and effects of these parameters. Four classes, totalling 40 male and 36 female undergraduates, listened to parts of two commercially available sets of relaxation tapes. Both sets offered progressive relaxation and autogenic training in a choice of a male or a female voice. One set also provided a musical and environmental background. Tape segments were randomly assigned to the classes and balanced for gender and background. Subjects indicated a preference for the female voices. In addition, there was a significant association between sex of subject and voice gender preference, with males preferring female voices and females preferring male voices. However, the choices of the "best" tapes and actual ratings of relaxation indicated no significant voice-gender preferences associations. Preferences for the facilitating effects of the tapes with musical and environmental backgrounds were reflected in significant preferences for tape sets, tape choices, and relaxation ratings. The clinical implications and limitations of these findings were discussed.
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http://dx.doi.org/10.2466/pms.1981.53.3.927 | DOI Listing |
Neurol Neuroimmunol Neuroinflamm
March 2025
Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney.
Background And Objectives: Despite the absence of acute lesion activity in multiple sclerosis (MS), chronic neurodegeneration continues to progress, and a potential underlying mechanism could be the kynurenine pathway (KP). Prolonged activation of the KP from chronic inflammation is known to exacerbate the progression of neurodegenerative diseases through the production of neurotoxic metabolites. Among the 8 KP metabolites, six of them, namely kynurenine (KYN), 3-hydroxylkynurenine (3HK), anthranilic acid (AA), kynurenic acid (KYNA), and quinolinic acid (QUIN), have been associated with neurodegeneration.
View Article and Find Full Text PDFPLoS Med
January 2025
University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Background: Nirmatrelvir with ritonavir (Paxlovid) is indicated for patients with Coronavirus Disease 2019 (COVID-19) who are at risk for progression to severe disease due to the presence of one or more risk factors. Millions of treatment courses have been prescribed in the United States alone. Paxlovid was highly effective at preventing hospitalization and death in clinical trials.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Gastroenterology, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Background: According to Rome IV, reflux hypersensitivity (RH) represents a novel form of functional esophageal disorder. This study was designed to compare the clinical features of three types of endoscopic-negative heartburn: RH, nonerosive reflux disease (NERD), and functional heartburn (FH).
Methods: Patients with heartburn in a medical center from 01/01/2017 to 10/31/2021 were included.
J Bone Joint Surg Am
January 2025
Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
Background: The relative advantages and disadvantages of 2-stage versus 1-stage management of infection following total hip arthroplasty (THA) are the current subject of intense debate. To understand the merits of each approach, detailed information on the short and, importantly, longer-term outcomes of each must be known. The purpose of the present study was to assess the long-term results of 2-stage exchange arthroplasty following THA in one of the largest series to date.
View Article and Find Full Text PDFJ Am Acad Orthop Surg Glob Res Rev
January 2025
From the Oakland University William Beaumont School of Medicine (Bitar, Zamzam, and Dr. Saleh), Rochester, MI; the Department of Orthopedic Surgery, University of Toledo Medical Center (Dr. Hasan), Toledo, OH; and Department of Orthopedic Surgery, Corewell Health (Dr. Saleh).
Background: Despite increasing diversity among medical students, pediatric orthopaedic surgery remains underrepresented regarding gender and ethnic diversity. Previous studies highlight notable underrepresentation of women and minorities in orthopaedic subspecialty fellowships.
Methods: This study analyzed data from 2013 to 2023 on pediatric orthopaedic surgery fellows, collected through the Accreditation Council for Graduate Medical Education and Graduate Medical Education Consensus.
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