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Purpose: Tranexamic acid administration into the epidural space has not been previously reported. We describe our experience managing and investigating a drug error involving incorrect route of tranexamic acid administration through an epidural catheter.

Clinical Features: A syringe containing tranexamic acid, intended for intravenous bolus and infusion intraoperatively using microbore tubing, was inadvertently attached to an epidural catheter via the Luer-type connector on the microbore tubing and epidural adapter.

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Several anatomical studies have described the morphology of the spinal space; however, researchers do not all agree on the presence of the dorsomedian ligamentous strand (DLS), which divides the epidural space. The possible existence of this structure still influences some clinical practice, such as locoregional anesthesia and pain therapy. Since the number of procedures occurring inside the epidural space have increased, this study's primary objective was to describe the composition of this space through epiduroscopy.

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Article Synopsis
  • - The study investigated pain levels after kidney tumor surgeries using different approaches: flank incision, transabdominal, and laparoscopy, focusing on 107 patients undergoing flank surgeries.
  • - Results indicated that laparoscopic surgeries resulted in higher immediate pain (T(0-2)) but significantly less pain thereafter compared to flank incisions, which showed increasing pain levels up to the seventh day post-surgery.
  • - Thoracic peridural analgesia (tPDA) was found to be the most effective pain management method for flank incisions, significantly reducing pain compared to conventional analgesics and patient-controlled analgesia.
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The treatment of pain after thoracic surgery is a challenge and takes place in the individual clinics mostly according to clinic internal standards. It exists no currently valid S3 guideline for the treatment of acute perioperative and posttraumatic pain. For an effective pain treatment as well individual pain experience as the pain intensity of the various thoracic surgical procedures must be considered.

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