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Unraveling the relationship between facial neuropathic conditions and pain, sleep, chronotypes, bruxism, and psychosocial factors.
Cranio
January 2025
Curso de Pós-Graduação em Neurociências, Instituto de Ciências Biológicas (ICB), Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.
Objective: This cross-sectional study evaluated associations between sleep disorders, pain, bruxism, and chronotypes in patients with trigeminal neuralgia (TN) or post-herpetic neuralgia (PHN) in orofacial area.
Methods: Ninety-four subjects (25 TN, 14 PHN, 55 controls) were evaluated for pain, sleep, chronotype, anxiety, depression, oral behaviors, and lifestyle by validated instruments. Bruxism was assessed by self-report.
Regulation of circadian gene activity in fibroblasts from ADHD patients through Rosiglitazone: a pilot study.
J Neural Transm (Vienna)
January 2025
Chair of Vascular Neurology, Dementia and Ageing, University Hospital Essen, Essen University Medical School, University of Duisburg-Essen, 45147, Essen, Germany.
Attention-deficit/hyperactivity disorder (ADHD) is a frequently observed condition, with about 70% of individuals diagnosed with ADHD experiencing irregular sleep-wake patterns. Beyond the primary symptoms of ADHD, there is a significant overlap with sleep-related issues, indicating that disrupted sleep patterns may exacerbate ADHD symptoms. ADHD-related sleep problems can be traced to a delayed circadian rhythm and a later onset of melatonin production.
View Article and Find Full Text PDFMitochondrial dynamics: molecular mechanism and implications in endometriosis.
Biochimie
January 2025
Department of Veterinary Sciences, University of Messina, 98168 Messina, Italy. Electronic address:
Endometriosis affects about 10% of women of reproductive age, leading to a disabling gynecologic condition. Chronic pain, inflammation, and oxidative stress have been identified as the molecular pathways involved in the progression of this disease, although its precise etiology remains uncertain. Although mitochondria are considered crucial organelles for cellular activity, their dysfunction has been linked to the development of this disease.
View Article and Find Full Text PDFIncidence of spontaneous Brugada ECG during follow-up in patients with drug-inducible pattern: a systematic review and meta-analysis.
Heart Rhythm
January 2025
Cardiovascular Disease Unit, IRCCS San Martino Polyclinic Hospital, Genoa, Italy; Department of Internal Medicine, University of Genoa, Italy.
Alpha and high beta subthalamic intermittent activity correlates with freezing of gait severity in Parkinson's disease.
Clin Neurophysiol
January 2025
Center of Engineering, Modeling and Applied Social Sciences, Federal University of ABC (UFABC), São Bernardo do Campo, Brazil; Brazilian Institute of Neuroscience and Neurotechnology, Campinas, São Paulo, Brazil. Electronic address:
Introduction: Freezing of gait (FOG) is a disabling symptom that affects over half of Parkinson's disease patients (PD) and hinders the ability to walk. Subthalamic nucleus (STN) deep brain stimulation (DBS) effectiveness in ameliorating the FOG remains controversial, lacking a reliable electrophysiological biomarker from local field potentials (LFP).
Methods: The LFP-STN rhythms bandpower and dynamics were characterized at rest across groups in a cohort of 23 patients (14 with FOG, and 9 without, n-FOG).
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