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Genomic data mining reveals the transaminase repertoire of () strain GS115 and supports a systematic nomenclature.
J Genet
June 2021
Department of Biochemical Engineering, University College London, Bernard Katz Building, London WC1E 6BT, UK.
Transaminases are an industrially important class of enzyme, due to their ability to catalyse amination reactions for production of chiral amines, and are key building blocks of small molecule pharmaceuticals. We analysed the genome of strain GS115 of the methylotrophic yeast , formerly known as , to identify the transaminase genes and propose a systematic nomenclature based on both phylogeny and structuro-functional features. is an increasingly attractive industrial host cell due to its ability to grow to high biomass, up to 60% wet cell weight by volume, using methanol as carbon source and inducer of transgene expression.
View Article and Find Full Text PDF[Structuro-functional basis of complex forms of higher nervous activity].
Zh Vyssh Nerv Deiat Im I P Pavlova
June 1986
[A further role on the structuro-functional organization of the vegetatovisceral manifestations of epilepsy (diencephalic epilepsy?)].
Zh Nevropatol Psikhiatr Im S S Korsakova
October 1982
The authors present the results of examining 138 patients whose disease could be classed with the so-called "diencephalic epilepsy" proceeding from the structure of the paroxysmal vegetovisceral manifestations, the degree of the neuroendocrinal syndromes, the complicate scope of the organic and functional anomalies, and hydrocephalus of the IIId ventricle. Stereoelectroencephalographic examinations made in the course of spontaneous vegetovisceral and polymorph seizures have shown that the aura correlates with the reaction of desynchronization in the deep and cortical structures of the brain; the specific manifestations of the seizures are combined with epileptic discharges in the limbic and neocortical structures and absence of the discharges in the thalamus and hypothalamus. It has been shown that the limbic system, the neocortical and truncal divisions of the brain take part in the structural and functional organization of the vegetovisceral paroxysms.
View Article and Find Full Text PDF[Structuro-functional organization of the vegetative (autonomic) nervous system].
Fiziol Zh SSSR Im I M Sechenova
July 1980
On the basis of a number of structural and functional indices, application of pharmacological analysis as well as recording of neuronal activity, the autonomic nervous system is subdivided into the sympathetic, parasympathetic and metasympathetic parts. The metasympathetic system includes the complex of microganglia situated in the walls of vosceral organs and having marked motility activity (the heart, ureters, intestine, stomach). According to the localization, separate areas of this system can be defined by its site (for example, the cardiometasympathetic area in the heart).
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