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Kimura disease of the tongue base: a rare case diagnosed through cytological examination of Warthin-Finkeldey-type multinucleated cells.
J Clin Exp Hematop
March 2025
Department of Diagnostic Pathology and Cytology, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka-city, Osaka, Japan.
Kimura disease (KD) is a rare chronic inflammatory condition that primarily affects Asian males and typically presents in the head and neck region. We describe an exceptionally rare case of KD involving the lingual tonsil of Waldeyer's ring in a 39-year-old Japanese man, marking only the second reported instance of lingual involvement and the first specifically affecting the tongue base. The patient presented with a well-circumscribed, 3.
View Article and Find Full Text PDFSevere Hypersensitivity Reactions with Oral Manifestations: Case Reports on Stevens-Johnson Syndrome and DRESS Syndrome.
J Pharm Bioallied Sci
December 2024
Department of Diagnostic and Surgical Dental Sciences, College of Dentistry/Gulf Medical University, Ajman, UAE.
Stevens-Johnson syndrome (SJS) and Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome are rare conditions, representing severe hypersensitivity reactions with significant oral presentations. SJS is an uncommon but severe variant of erythema multiforme, presenting skin and mucosal eruptions that can be potentially fatal. DRESS syndrome, similarly, involves a severe hypersensitivity reaction characterized by fever, rash, and organ involvement.
View Article and Find Full Text PDFRationale: Thymic stromal lymphopoietin (TSLP) and IL-33 are alarmins implicated in EoE pathogenesis by activating multiple cells including mast cells (MCs). Whether TSLP or IL-33 have a role in EoE and whether their activities are distinct requires further investigation.
Methods: Experimental EoE was induced in wild type (WT) and mice.
Eosinophilic esophagitis manifesting as intractable hiccups in an elderly patient: a case report.
J Med Case Rep
March 2025
Department of Gastroenterology, Faculty of Medicine, University of Balamand, El Koura, Balamand, Lebanon.
Background: Eosinophilic esophagitis is a condition characterized clinically by symptoms related to esophageal dysfunction and histologically by a marked eosinophilic infiltrate in the esophageal mucosa. The most typical symptoms of eosinophilic esophagitis include intermittent dysphagia with episodic food impaction and heartburn with propensity for young individuals. The relationship between hiccups and eosinophilic esophagitis is unclear but has been described.
View Article and Find Full Text PDFWhen Treatment Backfires: A Case Report of Sulfasalazine-Induced Hypersensitivity Syndrome in a Moroccan Patient With Crohn's Disease and Literature Review.
Cureus
February 2025
B2S Research Laboratory, Faculty of Medicine and Pharmacy, Cadi Ayyad University, Marrakech, MAR.
Sulfasalazine-induced hypersensitivity syndrome (SIHS) is a drug-specific variant of the syndrome known as drug reaction with eosinophilia and systemic symptoms (DRESS). It is a severe and unpredictable hypersensitivity reaction that can present with a spectrum of symptoms, ranging from mild rashes and unexplained fever to life-threatening systemic organ involvement. This diversity of symptoms often results in a diagnostic delay and/or misdiagnosis.
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