Three hundred and fifteen patients with chronic nonulcerative colitis were studied. Two hundred patients were given specific immunotherapy by bacterial allergens, and 115 formed the control group. Immunotherapy was carried out with increasing doses of bacterial allergens - E Coli, Streptococcus, Staphylococcus or Proteus - for 1-2 years. The effectiveness of immunotherapy was established toward the end of the course of treatment (as well as over a long period). The improvement was expressed clinically as a decrease in the endoscopic and coprologic signs of inflammation, an increase in natural immunologic resistance and a reduction of bacterial allergy and autoimmune disorders.
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