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Hypercalcemia Due to Progressive Disseminated Histoplasmosis.
JCEM Case Rep
November 2024
Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh 226014, India.
Hypercalcemia is a relatively common clinical problem, and evaluation for its etiology may often prove to be challenging. However, a thorough etiological workup can guide effective therapy and can often prove to be lifesaving. We describe a 61-year-old man who presented with fever, anorexia, and weight loss for 3 months, and altered sensorium for around 1 week.
View Article and Find Full Text PDFDisseminated adrenal histoplasmosis in an immunocompetent adult from Nepal: a case report.
Ann Med Surg (Lond)
October 2023
Kathmandu Medical College and Teaching Hospital, Kathmandu.
Introduction: Histoplasmosis is caused by the environmental fungus . In immunocompromised patients, histoplasmosis can present as a disseminated infection that can involve the liver, lymph nodes, lungs, and adrenal glands. Disseminated histoplasmosis affecting the adrenal glands in an immunocompetent individual is a rare infection.
View Article and Find Full Text PDFInfection of bats with Histoplasma species.
Med Mycol
August 2023
Manchester Fungal Infection Group, School of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Histoplasma species infect humans and animals, notably bats. Histoplasma species are thermally dimorphic fungi existing in mycelial form in the natural environment and in yeast form in infected tissues. In this narrative literature review, we summarize the occurrence of Histoplasma spp.
View Article and Find Full Text PDFHypoalbuminemia is a risk factor for invasive fungal infections and poor outcomes in infected kidney transplant recipients.
Clin Transplant
October 2023
Division of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Introduction: Invasive fungal infections (IFI), are estimated to occur in 2%-14% of kidney transplant recipients (KTRs) in the current era of immune suppression and are associated with high mortality rates. We hypothesized that hypoalbuminemia in KTRs is a risk factor for IFI and would be associated with poor outcomes.
Methods: In this study, using data from a prospective cohort registry, we describe the frequency of IFI due to Blastomycosis, Coccidioidomycosis, Histoplasmosis, Aspergillosis, and Cryptococcus in KTRs with serum albumin levels measured 3-6 months before diagnosis.
Chronic Tubercular Mediastinitis: A Rare Case Presentation With Subcutaneous Emphysema.
Cureus
May 2023
Respiratory Medicine, Datta Meghe Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND.
Tuberculosis, histoplasmosis, various fungal infections, malignancy, and sarcoidosis are the most common causes of chronic or slowly progressing mediastinitis. Chronic mediastinitis of tubercular origin with subcutaneous emphysema is exceptionally uncommon, and the majority of cases are caused by trauma. Here we report the case of a 35-year-old chronic alcoholic male who presented to the Outpatient Department (OPD) with complaints of cough, chest pain, loss of weight, and intermittent low-grade fever for three months with no significant past medical history or family history for any respiratory diseases.
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