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Chlorine Dioxide Dry Gas: A Promising Solution for Effective Decontamination of Cephalosporin Compounds.
Appl Biosaf
December 2024
Royal Society of Biology, London, United Kingdom.
Introduction: Cephalosporins can trigger hypersensitivity reactions in certain individuals. Consequently, strict regulations restrict the production of non-beta-lactam substances during or after cephalosporin manufacturing. Dry chlorine dioxide gas (dClO), together with ultra-performance liquid chromatography Mass spectrometry/mass spectrometry (UPLC-MS/MS) detection methods, has emerged as a promising method for decontaminating cephalosporin compounds.
View Article and Find Full Text PDFEstablishment of an Antimicrobial Stewardship Program to Spare the Use of Oral Fluoroquinolones for Acute Uncomplicated Cystitis in Outpatients.
Antibiotics (Basel)
September 2024
Department of Pharmacy, Musashino Red Cross Hospital, 1-26-1, Kyonancho, Musashino-shi, Tokyo 180-8610, Japan.
The increase in fluoroquinolone (FQ)-resistant (EC) is a serious global problem. In addition, much of acute uncomplicated cystitis (AUC) cases are caused by EC. FQs have been selected for the treatment of cystitis in outpatients, and there is concern about treatment failure.
View Article and Find Full Text PDFEfficacy and safety of first- and second-line antibiotics for cellulitis and erysipelas: a network meta-analysis of randomized controlled trials.
Arch Dermatol Res
September 2024
Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan, Hubei, 430022, P.R. China.
Article Synopsis
- - The study conducted a network meta-analysis to assess and rank the effectiveness of various first- and second-line antibiotics for treating cellulitis and erysipelas, analyzing data from 10 randomized clinical trials involving 1,936 patients up to July 2024.
- - For cellulitis, cefaclor had the best curative outcomes, while ceftriaxone was noted for having the fewest gastrointestinal side effects like diarrhea or vomiting.
- - In treating erysipelas, pristinamycin exhibited the highest cure rates but also carried a greater risk of causing rash, highlighting the need for further research on optimizing antibiotic choices for these skin infections.
Application of Cefaclor in Orthodontics through Micro-Implant Anchorage in Patients with Periodontitis.
Ann Ital Chir
June 2024
Department of Stomatology, First People's Hospital of Yongkang City, 321300 Yongkang, Zhejiang, China.
Aim: Chronic periodontitis leads to gingival swelling, hyperplasia, and tooth mobility, which affects orthodontic treatment. The aim of this study was to investigate the application of cefaclor in orthodontics through micro-implant anchorage in patients with periodontitis.
Methods: A retrospective study was conducted on patients with periodontitis who received micro-implant anchorage treatment in the department of orthodontics at the First People's Hospital of Yongkang City from July 2019 to January 2022.
Impact of the COVID-19 pandemic on Haemophilus influenzae infections in pediatric patients hospitalized with community acquired pneumonia.
Sci Rep
June 2024
Department of General Practice, Yongchuan Hospital of Chongqing Medical University, No. 439, Xuanhua Street, Chongqing, 402160, China.
The COVID-19 pandemic has altered the infection landscape for many pathogens. This retrospective study aimed to compare Haemophilus influenzae (H. influenzae) infections in pediatric CAP patients hospitalized before (2018-2019) and during (2020-2022) the COVID-19 pandemic.
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