During an observation period of 20 months (from January 1978 to September 1979) 123 children with clinically suspected salmonellosis were admitted to the Department of Pediatrics, 70 males and 53 females varying in age from 17 days to 14 years. S. typhi or S. enteriditis was isolated from the stool, urine, blood or cerebrospinal fluid in 85% (105/123) of the cases. The results of the microbiologic examination showed that 28 out of the 105 cases (27%) were resistant to chloramphenicol of which the S. sero-group C1 was predominant. It appeared that 28 cases conformed to the clinical data. In all these cases chloramphenicol was replaced by other antibiotics according to the sensitivity test. The mortality rate was 7% (9/123). Four of the fetal cases were from the chloramphenicol resistant group.
Dog bites are a source of zoonotic infections to humans, such as pasteurellosis and meningitis. Zoonotic bacterial identification and their antibiotic susceptibility assessment are key towards the successful management of such infections. This study isolated and identified zoonotic bacterial species from the oral cavities of indigenous dogs and also determined their antibiotic susceptibility profile.
This study emphasizes the potency of a bacteriocin screened from (MK733983) of ethnomedicinal origin. Antibiofilm analysis with 0.5-3x minimal bacteriocin concentrations with critical and highly prioritized standard microbes such as , , , , , and showed potential biofilm inhibition and eradication of ≥ 5-99%, ≥ 1-86% respectively that correlated with biofilm viable cell-count.
Background: The introduction of the 10-valent pneumococcal conjugate vaccine (PCV10) for nationwide childhood immunization in 2010 led to a significant reduction in colonization and invasive pneumococcal disease (IPD) by vaccine serotypes in young. However, non-vaccine serotypes have emerged, and serotype 19A is now the leading cause of IPD in Brazil.
Methods: We analyzed 32 serotype 19A isolates of Streptococcus pneumoniae recovered from children and adults who attended different health facilities in the state of Rio de Janeiro, Brazil, between 2010 and 2023.
We report for the first time whole-genome sequencing of four multidrug-resistant sequence type (ST) 307 recovered from patients in two hospitals in Armenia. Comparative genomic analysis revealed that the isolates were closely related, with a maximum of 39 single nucleotide polymorphism (SNP) differences in the core genome. All Armenian isolates carried the integrative and conjugative element ICE4, which bears the yersiniabactin locus, and shared a common evolutionary origin, diverging around 2005 (95% CI: 1999 to 2011).
Enteric fever is a significant health problem in developing countries caused by serovars Typhi and Paratyphi. Unfortunately, the burden of the disease remains high not only because of the complications related to the disease but also, especially, because of the spread of the strains of resistant to antibiotics. The aim of the present study was to evaluate the antibiotic resistance patterns of Typhi and Paratyphi clinical isolates as well as the risk factors associated with infection.
