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ENDOCRINOLOGICAL AND GYNECOLOGICAL PARAMETERS IN ASSESSING INFERTILITY AT REPRODUCTIVE AGE.
Acta Endocrinol (Buchar)
January 2025
Anesthesiology and Intensive Care Unit, Iasi, Romania.
Introduction: Infertility is a very discussed problem in many endocrinological and gynecological courses and congresses. In a rapidly revolving environment women tend to postpone pregnancy to have security in their financial life and career.We discuss primary and secondary infertility and the hormonal results in women that presented for a desire to conceive with their partner.
View Article and Find Full Text PDFImmune evasion through mitochondrial transfer in the tumour microenvironment.
Nature
January 2025
Division of Cell Therapy, Chiba Cancer Center Research Institute, Chiba, Japan.
Cancer cells in the tumour microenvironment use various mechanisms to evade the immune system, particularly T cell attack. For example, metabolic reprogramming in the tumour microenvironment and mitochondrial dysfunction in tumour-infiltrating lymphocytes (TILs) impair antitumour immune responses. However, detailed mechanisms of such processes remain unclear.
View Article and Find Full Text PDFFemale Brain and Endocrinological Research-Veteran (FemBER-Vet) study: A study protocol for identifying endocrinological, lifestyle and psychosocial determinants of brain health outcomes in female veterans for future intervention success.
PLoS One
January 2025
Female Brain & Endocrine Health Research (FemBER) Consortium.
Background: Recent studies have demonstrated a greater risk of dementia in female veterans compared to civilians; with the highest prevalence noted for former service women with a diagnosis of psychiatric (trauma, alcoholism, depression), and/or a physical health condition (brain injury, insomnia, diabetes). Such findings highlight the need for increased and early screening of medical and psychiatric conditions, and indeed dementia, in the female veteran population. Further, they call for a better understanding of the underlying biopsychosocial mechanisms that might confer heightened risk for female veterans, to tailor preventative and interventional strategies that support brain health across the lifespan.
View Article and Find Full Text PDFReproductive Physiology and Molecular Mechanisms Underlying Testicular Development and Spermatogenesis in Echinoderms: A Marine Invertebrate Deuterostomes.
Mol Reprod Dev
January 2025
The Key Laboratory of Mariculture, Ministry of Education, College of Fisheries, Ocean University of China, Qingdao, China.
Echinoderms exhibit a wide range of reproductive strategies as adaptations to variable environments. The processes of gonadal development, germ cell differentiation, and spermatogenesis in echinoderms are crucial physiological processes that warrant further in-depth exploration. This review systematically summarizes research from early basic sciences to recent studies on male gonadal development and spermatogenesis, encompassing morphology, histology, physiology, cell biology, developmental biology, and evolutionary biology.
View Article and Find Full Text PDFImpact of C-Reactive Protein-to-Albumin Ratio on Lung Cancer With Interstitial Pneumonia.
Ann Thorac Surg Short Rep
December 2024
Department of General Thoracic Surgery and Breast and Endocrinological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan.
Background: Lung cancer with interstitial pneumonia is known to be a refractory disease. We explored whether systemic inflammatory response markers are associated with outcomes in these patients.
Methods: The participants of this multicenter retrospective study, consisting of 17 medical institutions, were treatment-naïve patients with lung cancer combined with interstitial pneumonia who underwent surgical resection between 2012 and 2017.
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