The role of lymphstasis in atherogenesis.

Ann Thorac Surg

Published: March 1981

The cardiac lymphatics are responsible for the transport of all the lipoproteins and cholesterol from the extravascular myocardial tissue, although little is known about the filtration and lymphatic clearance of the coronary artery wall. It is postulated that a critical factor in the genesis of arteriosclerosis is lymphstasis, which adequately explains the positive correlation with the known risk factors for coronary artery disease and the negative correlation with high-density lipoproteins. Further research is necessary in this little-known area to better understand the etiology of atherosclerosis.

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0003-4975(10)60949-6DOI Listing

Publication Analysis

Top Keywords

coronary artery
8
role lymphstasis
4
lymphstasis atherogenesis
4
atherogenesis cardiac
4
cardiac lymphatics
4
lymphatics responsible
4
responsible transport
4
transport lipoproteins
4
lipoproteins cholesterol
4
cholesterol extravascular
4

Similar Publications

Background: The triglyceride glucose-body mass index (TyG-BMI) is considered to be a reliable surrogate marker of insulin resistance (IR). However, limited evidence exists regarding its association with the severity of coronary artery disease (CAD), particularly in hypertensive patients with different glucose metabolic states, including those with H-type hypertension. This study aimed to investigate the relationship between TyG-BMI and CAD severity across different glucose metabolism conditions.

View Article and Find Full Text PDF

Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by the presence of at least one cardiovascular disease (CVD) risk factor, underscoring its potential to elevate CVD risk in affected individuals. However, evidence linking MASLD to subclinical coronary atherosclerosis remains scarce, and further investigations are necessary to elucidate the independent role of varying MASLD severities as a CVD risk factor.

Methods: This study analyzed 7,507 participants aged ≥ 40 who underwent comprehensive health evaluations at the Shanghai Health and Medical Center.

View Article and Find Full Text PDF

U-Shaped Association Between Dietary Copper Intake and New-Onset Chronic Kidney Disease: A 30-Year Follow-Up Study From Young Adulthood to Midlife.

Mol Nutr Food Res

January 2025

Division of Nephrology, Nanfang Hospital, Southern Medical University, National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Guangdong Provincial Institute of Nephrology, Guangdong Provincial Key Laboratory of Renal Failure Research, Guangzhou, 510515, China.

Scope: The relationship of dietary copper intake with new-onset chronic kidney disease (CKD) remained unclear. We aimed to examine the association of dietary copper intake with new-onset CKD in a 30-year follow-up study from young adulthood to midlife.

Methods And Results: A total of 4038 U.

View Article and Find Full Text PDF

Background: Several studies have attempted to demonstrate the associations between body mass index (BMI) in early age and cardiovascular diseases (CVDs). However, their findings were inconsistent and inconclusive, indicating the need for further investigation.

Methods: We conducted a systematic review and meta-analysis of studies focusing on BMI in early age (age from 2 to 22) in relation to CVDs in adulthood, including coronary artery disease (CHD), ischemic and hemorrhagic stroke, myocardial infarction and heart failure.

View Article and Find Full Text PDF

Accuracy of pulse wave velocity for screening coronary artery disease: a systematic review and meta-analysis.

Diagnosis (Berl)

January 2025

CarVasCare Research Group, Facultad de Enfermería de Cuenca, 16733 Universidad de Castilla-La Mancha , Cuenca, Spain.

Coronary artery disease (CAD) is the leading cause of cardiovascular events and showed high prevalence and healthcare costs in 2019. However, CAD screening for cardiovascular event prevention is invasive and expensive. This study aims to estimate the ability of a noninvasive method, pulse wave velocity (PWV), to detect the presence or absence of coronary artery disease in patients with suspected CAD.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!