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A Comparative Study of Vitamin D Serum Levels in Monosymptomatic Enuretic Children and Non-Enuretic Children.
Neurourol Urodyn
January 2025
Urology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Background: Enuresis refers to urinary incontinence during sleep in children over 5 years of age. The pathogenesis of enuresis is complex. It is related to low functional bladder capacity, nocturnal bladder overactivity, and high arousal threshold, and it is also related to the immaturity of the central nervous system.
View Article and Find Full Text PDFA Case of Hyponatremic Hypertensive Syndrome With Neurologic Sequelae Secondary to Unilateral Renal Artery Stenosis.
Cureus
September 2024
Internal Medicine, Dayton Veteran's Affairs Medical Center (Wright State University Internal Medicine Associate Faculty), Dayton, USA.
Article Synopsis
- Unilateral renal artery stenosis can lead to a rare and serious condition known as hyponatremic hypertensive syndrome (HHS), which presents with low sodium levels and high blood pressure.
- A case study highlights a 62-year-old man experiencing HHS during a hypertensive emergency complicated by encephalopathy.
- Early diagnosis and management focusing on fluid and electrolyte balance are crucial to reduce complications and enhance patient outcomes.
Implications of Dysnatremia and Endocrine Disturbances in COVID-19 Patients.
Int J Mol Sci
September 2024
Clinical Institute of Nuclear Medicine and Radiation Protection, University Hospital Centre Osijek, 4 Josip Huttler Street, HR-31000 Osijek, Croatia.
Article Synopsis
- - Sodium imbalance is a frequent issue in COVID-19, often caused by hormonal disruptions, particularly involving conditions like hypothyroidism and hypocortisolism, which can both lead to lower sodium levels (hyponatremia).
- - Hypocortisolism, resulting from adrenal or pituitary issues, affects the kidneys' ability to excrete water properly and increases the secretion of antidiuretic hormone (ADH), further diluting sodium levels.
- - The review emphasizes that the relationship between COVID-19 and sodium imbalance is complicated by factors like the renin-angiotensin-aldosterone system (RAAS) being impacted by the virus, highlighting the need for more research to better manage these disturbances in affected
The effect of liver surgery and fluid strategy on renin activity and aldosterone and anti-diuretic hormone levels: a secondary analysis of the GALILEO trial.
HPB (Oxford)
October 2024
Department of Anesthesiology, Amsterdam University Medical Centre, Amsterdam, the Netherlands; Amsterdam Cardiovascular Sciences Research Institute, Amsterdam University Medical Centre, Amsterdam, the Netherlands.
Background: It is unknown whether liver surgery leads to increased RAAS activity and anti-diuretic hormone (ADH) levels and subsequent fluid accumulation. Furthermore, it is unknown whether the peri-operative fluid strategy changes this effect.
Methods: This is a pre-planned post hoc analysis of a randomised controlled trial which compared restrictive (n = 20) versus liberal fluid strategy (n = 20) in patients undergoing liver surgery.
Short-Lived Active Prorenin: Precursor of So-Called Native Prorenin.
Hypertension
June 2024
Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands (M.A.D.H.S., A.H.J.D.).
The enzymatic activity of the aspartic protease, renin, is critical for its function in blood pressure regulation and sodium homeostasis. Incubation of so-called native prorenin at low pH leads to its activation. After binding to transition-state mimicking renin inhibitors at neutral pH, prorenin attains the active conformation, as indicated by immunosorbent assay using monoclonal antibodies specific for epitopes of the prosegment or the renin body.
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