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Despite the EU legislation regulating the circulation of dietary and food supplements within the internal market, the system of state control requires improvement. For instance, due to existing regulatory gaps, certain pharmaceutical entities commit violations of regulatory requirements, such as failing to register medicinal products and selling them under the guise of dietary and/or food supplements. Conversely, physicians may recommend ordinary dietary and food supplements to patients as if they were medicinal products.
View Article and Find Full Text PDFPrevalence, predictors, and mortality of Super-Fontan patients in a single-centre nationwide cohort.
Cardiol Young
January 2025
Children's Heart Centre, Motol University Hospital, Prague, Czech Republic.
Aims: To evaluate the prevalence, long-term mortality, and clinical characteristics in total cavopulmonary connection patients with excellent functional outcomes.
Methods And Results: A retrospective study of cardiopulmonary exercise test results in 288 patients after total cavopulmonary connection from a single-centre nationwide database. A subgroup of 88 (30.
The Presence of Small-Size Circulating Tumor Cells Predicts Worse Prognosis in Non-Small Cell Lung Cancer Patients.
Arch Pathol Lab Med
February 2025
Department of Clinical Laboratory, Haikou People's Hospital, Haikou Affiliated Hospital of Central South University Xiangya School of Medicine, Haikou, Hainan, China.
Endovascular Thrombectomy for Extracranial Internal Carotid Artery Occlusions With Large Ischemic Strokes: Insights From the SELECT2 Trial.
Neurology
February 2025
Department of Neurology, Department of Stroke, University Hospital Cleveland Medical Center, Case Western Reserve University, Cleveland, OH.
Background And Objectives: Although previous trials have established the efficacy and safety of endovascular thrombectomy (EVT) in large ischemic core strokes, most of them excluded patients with extracranial internal carotid artery (e-ICA) occlusion. We aimed to compare outcomes in patients with e-ICA occlusion and large ischemic core infarcts treated with EVT vs medical management (MM).
Methods: This was a secondary analysis of the SELECT2 trial, a randomized controlled trial conducted at 31 international sites.
The Presence of a Shelter in an Open Field Test Has Differential Effects on the Behavior and Stress Response of Two Mouse Species.
J Exp Zool A Ecol Integr Physiol
January 2025
Departamento de Biologia, Faculdade de Ciências, Universidade de Lisboa, Lisboa, Portugal.
The open field test (OFT) is frequently used in research to assess anxiety-like behavior and locomotor activity. Its simple design can lead to the misconception that it is a standardized procedure comparable between laboratories. However, some modifications in the setup can cause changes in behavior.
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