By using fluorescent probes it was shown that hydrocortisone, cortisone and estron decrease the constant of the probe binding with dimethylaminochalcone in the lipid membranes proportional to the distribution coefficient of steroids in the system lipids-water. It is only hydrocortisone and, to a lesser extent, cortisone which produce such an effect in the plasmatic membranes of the hepasytes. The presence of a "preference system" for corticosteroids is presumed in the membranes.

Download full-text PDF

Source

Publication Analysis

Top Keywords

["system recognition"
4
recognition" "system
4
"system preference"
4
preference" corticosteroids
4
corticosteroids hepatocyte
4
hepatocyte plasmatic
4
plasmatic membrane]
4
membrane] fluorescent
4
fluorescent probes
4
probes hydrocortisone
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!