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Nutrition in the critically ill in resource-limited settings/low- and middle-income countries.
Curr Opin Clin Nutr Metab Care
January 2025
Department of Anaesthesiology and Critical Care Medicine, Kepler University Hospital and Johannes Kepler University Linz, Linz, Austria.
Purpose Of Review: To share current concepts and provide an overview of the contextual issues and nutrition practices in critically ill patients in resource-limited settings (RLSs)/low- and middle-income countries (LMICs). Most of the world's population reside in these settings which also carries the greatest burden of critical illness.
Recent Findings: There is a paucity of evidence on nutrition practice in critically ill patients in RLSs and international guidelines are largely based on evidence derived from high-income countries (HICs).
A critical review of heat pump adoption in empirical and modeling literature.
iScience
January 2025
Colorado State University, Fort Collins, CO 80523, USA.
Household electrification is an important pillar of decarbonization in the US and requires the rapid adoption of electric heat pumps. Household energy models that project adoption rates do not represent these decisions well. To what extent are they limited by fundamental knowledge gaps, or is there scope to incorporate insights from the social science literature? We review the energy modeling and social science literature on heating equipment adoption to synthesize our understanding of adoption decisions, to identify best practices on representing decision-making behavior among energy models, and to suggest model improvements.
View Article and Find Full Text PDFAnticancer activity of , a rare and endemic species of holly in Northeast India, against murine lymphoma.
Heliyon
January 2025
DBT-BUILDER National Laboratory, Department of Life Sciences, Pachhunga University College, Aizawl, 796001, Mizoram, India.
Purkay. is a lesser-known species of holly (family Aquifoliaceae) that is endemic to Northeast India. Designated as critically endangered, the plant is used in the treatments of bacterial infections, cancer, intestinal helminthiasis, tuberculosis, and viral infections.
View Article and Find Full Text PDFATP Binding and Inhibition of Intrinsically Disordered Protein Interactions.
Langmuir
January 2025
Zhejiang Province Key Laboratory of Quantum Technology and Device, School of Physics, Zhejiang University, Yuhangtang Road 866, Hangzhou 310058, China.
Recent studies have shown that ATP at high physiological concentrations (>5 mM) can inhibit liquid-liquid phase separation (LLPS) driven by interactions between intrinsically disordered proteins (IDPs). However, the mechanism underlying such inhibitory effect still remains elusive. Here, we used all-atom molecular dynamics simulation to study the interaction of ATP with two typical IDPs (i.
View Article and Find Full Text PDFZwitterionic Hydrogels: From Synthetic Design to Biomedical Applications.
Langmuir
January 2025
State Key Laboratory of Separation Membranes and Membrane Processes, Key Laboratory of Hollow Fiber Membrane Materials and Membrane Processes (MOE), & Tianjin Key Laboratory of Hollow Fiber Membrane Materials and Processes, School of Materials Science and Engineering, Tiangong University, Tianjin, 300387, China.
Zwitterionic hydrogels have emerged as a highly promising class of biomaterials, attracting considerable attention due to their unique properties and diverse biomedical applications. Zwitterionic moieties, with their balanced positive and negative charges, endow hydrogels with exceptional hydration, resistance to nonspecific protein adsorption, and low immunogenicity due to their distinctive molecular structure. These properties facilitate various biomedical applications, such as medical device coatings, tissue engineering, drug delivery, and biosensing.
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