The dynamics of changes of the general, "non-sedimenting" activity of organelle-specific enzymes as well as their activity in perfusate during hypothermal conservation of the liver were studied in 77 experiments by the method of continuous and discontinuous perfusion, without perfusion and during the period of normal thermally artificial blood circulation after 3 hours of the organ conservation. The complex of enzyme tests including the assessment of "non-sedimenting activity" of mitochondrial glutamatdehydrogenase and lysosomal acid desoxiribonuclease during the conservation period was found to be an adequate criterion of the liver conservation quality. After the recovery of the artificial blood flow in the conservated organ the conservation quality is also assessed by their activity in the perfusate, in addition to determination of urokinase activity in the perfusate.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Preparation and characterization of a rat uterine decellularized scaffold.
Gland Surg
December 2024
Department of Gynecology, Wenzhou People's Hospital, Wenzhou, China.
Background: Infertility is a special reproductive health defect. For women, congenital uterine malformations, extensive adhesions in the uterine cavity, and hysterectomy are associated with infertility. Uterine transplantation is technically feasible, but its clinical application and development are limited by donor shortages and immune rejection.
View Article and Find Full Text PDFThe effect of power-based control on the haemodynamics and valve function of the biventricular assist circulation system.
Int J Artif Organs
January 2025
School of Electrical and Information Engineering, Jiangsu University, Zhenjiang, China.
Biventricular assist devices (BiVAD) are capable of providing mechanical support to the left and right ventricles to improve blood supply in heart failure, thereby maintaining patients' lives and improving their quality of life. But there is evidence that the incidence of aortic valve incompetence and other valvular pathologies is related to BiVAD support. Such as constant speed (CS) control may cause the valve to close completely and lose its normal valve function.
View Article and Find Full Text PDFLeg Blood Flow During Exercise with Blood Flow Restriction: Evidence for and Implications of Compensatory Cardiovascular Mechanisms.
J Appl Physiol (1985)
January 2025
School of Kinesiology and Health Studies, Queen's University, Kingston, Ontario, Canada.
Proximal limb cuff inflation to 40% arterial occlusion pressure (AOP) is assumed to reduce exercising leg perfusion, creating "blood flow restriction" (BFR). However, no study has validated this assumption. 18 healthy young participants (9F) performed two-legged knee flexion/extension exercise at 25% WRpeak with bilateral cuffs applied to the proximal thigh at 0% AOP (CTL), 20% AOP and 40% AOP.
View Article and Find Full Text PDFAnomalous Aortic Origin of a Coronary Artery in Pediatric Patients.
Curr Pediatr Rep
May 2024
Coronary Artery Anomalies Program, Division of Cardiology, Texas Children's Hospital, 6651 Main Street MC-E1920, Houston, TX 77030 USA.
Purpose Of Review: We present a contemporary approach to risk assessment and management of patients with anomalous aortic origin of a coronary artery (AAOCA).
Recent Findings: Anomalous left coronary artery from the right aortic sinus (L-AAOCA) with interarterial course carries a high risk of sudden cardiac death (SCD); therefore, current guidelines recommend exercise restriction and surgical intervention. Recent data in intraseptal and juxtacommissural L-AAOCA showed inducible perfusion abnormalities, leading to consideration of surgical intervention.
Resting state BOLD-perfusion coupling patterns using multiband multi-echo pseudo-continuous arterial spin label imaging.
Sci Rep
January 2025
Department of Radiology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.
The alteration of neurovascular coupling (NVC), where acute localized blood flow increases following neural activity, plays a key role in several neurovascular processes including aging and neurodegeneration. While not equivalent to NVC, the coupling between simultaneously measured cerebral blood flow (CBF) with arterial spin labeling (ASL) and blood oxygenation dependent (BOLD) signals, can also be affected. Moreover, the acquisition of BOLD data allows the assessment of resting state (RS) fMRI metrics.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!