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Clinicopathologic Spectrum of Secondary Solid Tumors of the Prostate of Nonurothelial Origin: Multi-institutional Evaluation of 85 Cases.
Am J Surg Pathol
September 2022
Department of Pathology, Johns Hopkins University, Baltimore, MD.
Secondary involvement of the prostate by urothelial or hematolymphoid neoplasms is relatively common and well-described. In contrast, less is known about the clinicopathologic spectrum of secondary solid tumors of the prostate of nonurothelial origin. This study evaluated a series of secondary nonurothelial solid tumors of the prostate diagnosed at 21 institutions.
View Article and Find Full Text PDFNTRK -Rearranged Uterine Sarcomas: Clinicopathologic Features of 15 Cases, Literature Review, and Risk Stratification.
Am J Surg Pathol
October 2022
Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA.
NTRK -rearranged uterine sarcomas are rare spindle cell neoplasms that typically arise in the uterine cervix of young women. Some tumors recur or metastasize, but features which predict behavior have not been identified to date. Distinguishing these tumors from morphologic mimics is significant because patients with advanced stage disease may be treated with TRK inhibitors.
View Article and Find Full Text PDFPatella-Femoral Joint Revision Surgery Following a Rare and Interesting Case of Implant Failure: A Case Report and Retrospective Analysis of Our Hospitals Implant Data.
Cureus
March 2022
Trauma and Orthopaedics, Royal Glamorgan Hospital, Llantrisant, GBR.
According to the national joint registry, patello-femoral joint (PFJ) replacement accounts for 1% of all knee arthroplasty procedures in the UK, 1014 of which were performed in 2018. The femoro-patella vialla (FPV) implant by MicroPort orthopaedics has a high reported rate of revision, more than four times that of other knee replacements. The mechanisms of failure are usually loss of fixation at the bone-implant interface.
View Article and Find Full Text PDFAssociation of COVID-19 vaccines ChAdOx1 and BNT162b2 with major venous, arterial, or thrombocytopenic events: A population-based cohort study of 46 million adults in England.
PLoS Med
February 2022
BHF Data Science Centre, Health Data Research UK, London, United Kingdom.
Background: Thromboses in unusual locations after the Coronavirus Disease 2019 (COVID-19) vaccine ChAdOx1-S have been reported, although their frequency with vaccines of different types is uncertain at a population level. The aim of this study was to estimate the population-level risks of hospitalised thrombocytopenia and major arterial and venous thromboses after COVID-19 vaccination.
Methods And Findings: In this whole-population cohort study, we analysed linked electronic health records from adults living in England, from 8 December 2020 to 18 March 2021.
Near-occlusion is difficult to diagnose with common carotid ultrasound methods.
Neuroradiology
May 2021
Department of Medical Imaging, Sunnybrook Health Science Center, University of Toronto, Toronto, Canada.
Purpose: To assess the sensitivity and specificity of common carotid ultrasound method for carotid near-occlusion diagnosis.
Methods: Five hundred forty-eight patients examined with both ultrasound and CTA within 30 days of each other were analyzed. CTA graded by near-occlusion experts was used as reference standard.
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