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C-X-C motif chemokine receptor 4-directed PET signal in the arterial tree is not consistently linked to calcified plaque burden and cardiovascular risk.
Theranostics
January 2025
Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
To establish the extent, distribution and frequency of in-vivo vessel wall [Ga]Ga-PentixaFor uptake and to determine its relationship with calcified atherosclerotic plaque burden (CAP) and cardiovascular risk factors (CVRF). 65 oncological patients undergoing [Ga]Ga-PentixaFor PET/CT were assessed. Radiotracer uptake (target-to-background ratio [TBR]) and CAP burden (including number of CAP sites, calcification circumference and thickness) in seven major vessel segments per patient were determined.
View Article and Find Full Text PDFReproductive success and offspring survival decline for female elephant seals past prime age.
J Anim Ecol
November 2024
Department of Ecology and Evolutionary Biology, University of California, Santa Cruz, California, USA.
Maternal age can influence reproductive success and offspring fitness, but the timing, magnitude and direction of those impacts are not well understood. Evolutionary theory predicts that selection on fertility senescence is stronger than maternal effect senescence, and therefore, the rate of maternal effect senescence will be faster than fertility senescence. We used a 36-year study of northern elephant seals (Mirounga angustirostris) to investigate reproductive senescence.
View Article and Find Full Text PDFRisk factors for adverse events after clavicle fracture open reduction and internal fixation: A NSQIP study.
Injury
November 2024
Virginia Commonwealth University Health System, Department of Orthopaedic Surgery, Richmond, VA, USA.
Article Synopsis
- * A review of over 6,700 patients undergoing ORIF revealed that 1.9% experienced complications within 30 days, with surgical site infections (SSI) occurring in 0.77% of cases, while current smoking and older age were significant risk factors for adverse events.
- * The research concluded that certain demographic factors, like being a current smoker or older, increase the likelihood of complications, whereas receiving treatment as an outpatient offered some protection against these adverse events.
Readmission within 30-days of open reduction and internal fixation for ankle fractures: NSQIP analysis of 29,905 patients.
J Orthop Surg Res
September 2024
Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, USA.
Background: Historically, ankle fractures have been treated with open reduction and internal fixation (ORIF) procedures, which are considered safe and effective. Patient characteristics may contribute to postoperative difficulties thereby increasing risk of hospital readmission. The objective of this study was to determine the frequency of and reasons for 30-day readmission and postoperative complications following ORIF for ankle fractures.
View Article and Find Full Text PDFBackground: Musculoskeletal conditions currently affect more than one-third of the US population and orthopedic procedures play a pivotal role in managing them. Like any invasive intervention, these carry a wide spectrum of risk, necessitating a comprehensive understanding of the associated morbidity and mortality. This study sought to provide a global perspective of the risks and complications associated with these procedures to establish an easy to understand risk stratification tool for both patients and providers.
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