Postpericardiotomy syndrome is an immune phenomenon that occurs from several days to months after surgical incision of the pericardium. Prominent clinical features include fever, pericarditis, and pleuritis. Of 161 patients with Wolff-Parkinson-White syndrome who underwent surgical treatment, 50 (31%) developed postpericardiotomy syndrome 4-12 days later. Of these 50 patients, 38 had sufficiently complete records for analysis. Significant radiographic abnormalities were present in 30 (79%) of these 38 patients, pericardial effusions in 19 (50%), pleural effusions in 26 (68%), and pulmonary infiltrates in four (10%). These radiographic signs almost always developed within 2 days of the onset of symptoms, either before or after, and were essentially absent in the 76 patients who did not clinically develop the syndrome. Postoperative radiographs can be extremely valuable in first suggesting or confirming the suspicion of postpericardiotomy syndrome.

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http://dx.doi.org/10.2214/ajr.138.3.503DOI Listing

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Purpose Of Review: This review aims to evaluate current diagnostic and therapeutic strategies for postpericardiotomy syndrome (PPS), with a focus on the evolving role of multimodality imaging, including echocardiography, cardiac computed tomography (CCT), and cardiac magnetic resonance imaging (CMR). The review also explores the potential benefits of advanced imaging in improving the accuracy and management of PPS.

Recent Findings: PPS, a common complication following cardiac surgery, presents with pleuritic chest pain, fever, and pericardial or pleural effusion.

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We appreciate the concerns raised by Ali. As well recognized, Post-Pericardiotomy Syndrome (PPS) has been a very difficult syndrome to classify and understand in part relating to variable methodologic approaches in the literature, and any attempts to clarify and unify methodology will only aid in better understanding this entity. Below is a point-by-point response to concerns raised.

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Article Synopsis
  • The article critiques Hyberg et al.'s study on early ECG changes predicting postoperative complications after atrial septal defect repair, expressing appreciation for their insights.
  • The author raises concerns about the methodology, particularly the use of ESC criteria without pediatric-specific considerations and the narrow focus on certain ECG indicators.
  • Suggestions for future research include incorporating standardized timing for ECGs and addressing independent risk factors for Post-Pericardiotomy Syndrome to enhance diagnostic strategies.
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