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Recalcitrant Pustular Dermatosis Successfully Treated With Prolonged Isotretinoin Therapy.
Cureus
November 2024
Dermatology, Imperial Dermatology, Hollywood, USA.
Isotretinoin (13-cis-retinoic acid) is a well-established systemic treatment for moderate to severe acne vulgaris, renowned for its ability to target multiple contributors to acne pathogenesis. However, its therapeutic potential extends beyond conventional acne management. This case report highlights its efficacy in treating recalcitrant pustular dermatosis, a condition that proved resistant to standard therapies and posed significant diagnostic challenges.
View Article and Find Full Text PDFImmunohistochemical Analyses of Monkeypox Skin Lesions with MPXV A29 and A35 Antibodies: A Novel Insight for Clinical-Histopathological Forms.
Jpn J Infect Dis
October 2024
Department of Sexually Transmitted Disease, Shanghai Skin Disease Hospital, Tongji University School of Medicine, China.
The aim of this study was to describe the clinical, histopathological, and immunohistochemical characteristics of MPX and offer meaningful insights into the clinicopathology of MPX. We recruited eight men who had sex with men diagnosed with MPX based on positive results from MPX Virus (MPXV)-specific polymerase chain reaction. Skin biopsies were obtained from four selected lesions, including typical and atypical lesions.
View Article and Find Full Text PDFNovel association of eosinophilic pustular folliculitis with systemic lupus erythematosus: A case report.
JAAD Case Rep
October 2024
Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas.
Two cases of eosinophilic pustular folliculitis successfully treated with abrocitinib.
J Dermatol
December 2024
Dermatology Hospital of Southern Medical University, Guangzhou, China.
Article Synopsis
- Eosinophilic pustular folliculitis (EPF) is a rare inflammatory skin disease mainly involving eosinophils and can appear in both follicle areas and less commonly in follicle-free areas.
- This case study details two patients with difficult-to-treat EPF who had previous treatment failures with various standard therapies.
- Both patients responded positively to the medication abrocitinib, achieving complete remission in one week and four weeks, with no side effects reported, suggesting it could be a safe treatment option for EPF.
Mepolizumab therapy for eosinophilic pustular folliculitis (Ofuji disease).
J Eur Acad Dermatol Venereol
November 2024
Dermatology Clinic, Maggiore Hospital, University of Trieste, Trieste, Italy.
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