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Article Synopsis
  • Angiodysplasia (AD) is a vascular condition in the gastrointestinal tract that often causes lower GI bleeding, especially in the elderly, and can be challenging to detect during endoscopy.
  • An 82-year-old woman with recurrent melena and anemia underwent various evaluations including contrast-enhanced CT scans, leading to a diagnosis of colonic AD after surgery.
  • The case emphasizes that contrast-enhanced CT is a safer and more convenient diagnostic tool for identifying AD-related bleeding in frail, elderly patients compared to traditional methods.
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Gastrointestinal endoscopic image analysis presents significant challenges, such as considerable variations in quality due to the challenging in-body imaging environment, the often-subtle nature of abnormalities with low interobserver agreement, and the need for real-time processing. These challenges pose strong requirements on the performance, generalization, robustness and complexity of deep learning-based techniques in such safety-critical applications. While Convolutional Neural Networks (CNNs) have been the go-to architecture for endoscopic image analysis, recent successes of the Transformer architecture in computer vision raise the possibility to update this conclusion.

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Epidemiology and risk factors for angiodysplasias of the upper and lower gastrointestinal tract: A large population-based study.

Dig Liver Dis

August 2024

The Gonczarowski Family Institute of Gastroenterology and Liver Diseases, Shamir (Assaf Harofeh) Medical Center, School of Medicine Faculty of Medical and Health Sciences, Tel Aviv University, Zerifin, Israel.

Article Synopsis
  • Gastrointestinal angiodysplasia (GIAD) is a rare condition, with an overall prevalence of 0.092%, primarily affecting older adults, particularly those aged 71-80, where the prevalence peaks at 0.37%.
  • A study identified significant risk factors for GIAD, including liver cirrhosis, hypertension, and aortic stenosis, along with demographic factors like female gender, and noted that GIADs are less common in patients with malignancies.
  • Understanding the associated clinical conditions and demographics of GIAD can aid in better recognizing its causes and developing effective treatment strategies for this rare gastrointestinal issue.
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Heyde's syndrome (HS) represents an association between aortic stenosis and intestinal angiodysplasias, and it has been demonstrated that acquired von Willebrand disease plays a pivotal role in the pathophysiology of this syndrome. In patients with HS, von Willebrand factor deficiency represents an additional risk factor, further contributing to the risk of bleeding and anemia. We present the case of an 86-year-old patient diagnosed with HS and von Willebrand deficiency in 2018.

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