Graves' ophthalmopathy is frequently a diagnostic and therapeutic dilemma for practicing ophthalmologists. We have reviewed the clinical immunology of this disorder with regard to clinical manifestations, humoral immunity, and cellular immunity. Special emphasis with applicable clinical and laboratory data is given to the hypothesis that Graves' thyrotoxicosis and ophthalmopathy may be frequently associated diseases rather than disorders caused by a common pathogenetic mechanism. Dysthyroidism may be the substrate for the development of the ophthalmopathy, but the two disorders probably are caused by different immunopathogenetic mechanisms.

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0161-6420(81)34992-6DOI Listing

Publication Analysis

Top Keywords

clinical immunology
8
graves' ophthalmopathy
8
ophthalmopathy frequently
8
disorders caused
8
clinical
4
immunology graves'
4
ophthalmopathy
4
ophthalmopathy graves'
4
frequently diagnostic
4
diagnostic therapeutic
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!