Patients with generalized histiocytosis X may be divided into three prognostic groups based on age at the time of diagnosis and presence or absence of organ dysfunction. These variables are independent. Favorable response to initial chemotherapy was shown to be associated with improved survival and overall disease control.

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http://dx.doi.org/10.1002/1097-0142(19810215)47:4<798::aid-cncr2820470427>3.0.co;2-jDOI Listing

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