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Bile lakes in patients with biliary atresia who presented with jaundice-free native liver survival indicating the risk of subsequent liver transplantation due to various factors.
Pediatr Surg Int
July 2024
Department of Rare/Intractable Cancer Analysis Research, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.
Article Synopsis
- * Out of 97 patients, 29 were excluded, leaving 48 living with their native liver and 20 who received transplants after one year, with bile lake identified as the strongest risk factor for liver transplant.
- * The findings suggest that bile lake can lead to serious complications, highlighting its significance as a risk factor for those with biliary atresia who maintain their native liver for a year post-surgery.
Laparoscopic versus open Kasai procedure for biliary atresia: long-term results of a randomized clinical trial.
Pediatr Surg Int
February 2023
Department of Surgery, National Children Hospital, Hanoi, Vietnam.
Purpose: The role of the laparoscopic approach for the Kasai procedure in the management of biliary atresia is still controversial. The aim of this study is to compare the long-term results of the laparoscopic Kasai procedure (LKP) to the open Kasai procedure (OKP).
Methods: A randomized clinical trial was carried out from October 2009 to March 2017.
Article Synopsis
- Alagille syndrome (ALGS) is a complex disorder that varies in how it affects individuals, and this study looked at clinical outcomes and genetic factors in 25 children over 7.3 years.
- About 36% of the children in the jaundice-free (JF) group had better health outcomes compared to those with progressive disease (PD), who had more serious issues and higher need for liver transplants.
- The study found distinct genetic mutations in the ALGS patients and highlighted that they generally had less severe liver damage and more growth challenges compared to children with biliary atresia at the time of liver transplant.
A preliminary single-center investigation of percutaneous biliary stenting in malignant hilar biliary obstruction: what impacts the clinical success and the long-term outcomes?
Support Care Cancer
November 2021
Department of Radiology, Shengjing Hospital of China Medical University, Huaxiang Road 39, Shenyang City, 110004, Liaoning Province, China.
Purpose: The purpose of this study is to investigate the influencing factors that may impact the clinical success, jaundice-free time, and overall survival in patients of malignant hilar biliary obstruction (MHBO) treated with a self-expanding metallic stent (SEMS).
Materials And Methods: Patients diagnosed with MHBO and treated with SEMS through percutaneous access from 1 Jul. 2013 to 1 Jul.
Risk Prediction Scoring System to Predict the Postsurgical Outcomes of Biliary Atresia.
J Indian Assoc Pediatr Surg
September 2020
Department of Paediatric Surgery, Lilavati Hospital and Research Centre, Mumbai, Maharashtra, India.
Aim: To find out association between liver function, liver histopathology and outcomes of biliary atresia (BA) following Kasai Portoenterostomy (KPE).
Materials And Methods: This is a retrospective study of children who underwent KPE at a single institute by single surgeon. The patient records analyzed and data of complete blood counts, liver function tests, coagulation profile and histopathology reports collected.
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