Embryogenesis of the hemopoietic tissue was histologically studied in Rana temporaria at successive developmental stages, beginning from neurula and up to the end of metamorphosis. Primary foci of hemopoiesis (yolk sac, pronephros, hepatic diverticulum) were also studied radioautographically. Histological description of the hemopoietic tissue in R. temporaria is presented according to common stages of development in the species investigated. The data concerning the early and, in fact, simultaneous appearance of primary blood cells (PBC) in embryonic foci, as well as the results of the radioautographic investigation on the dynamics of PBC proliferation demonstrate that there possibly exist some local sources of hemopoiesis in embryonic hemopoietic organs.

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