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Similar Publications

French protocol for diagnosis and management of Cogan's syndrome.

Rev Med Interne

October 2024

Service de médecine interne, hôpital Saint-Antoine, AP-HP, Sorbonne université, 184, rue du Faubourg-Saint-Antoine, 75012 Paris, France. Electronic address:

Article Synopsis
  • * It typically affects Caucasians equally across genders and can also be associated with other autoimmune diseases like polyarteritis nodosa.
  • * While ocular symptoms often have a good prognosis with potential recovery of vision, cochleo-vestibular issues can lead to serious and irreversible hearing loss, and treatment options are not well-established due to the condition's rarity.
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Phenotyping vestibulocochlear manifestations in Susac syndrome: a cohort study.

Eur Arch Otorhinolaryngol

October 2024

Department of Otorhinolaryngology, Department of Head and Skin, Ghent University Hospital, Ghent, Belgium.

Article Synopsis
  • The study aims to understand how the vestibulocochlear system is affected in patients with Susac syndrome (SuS), which is a rare condition that impacts the brain, eyes, and inner ear.
  • A review of 21 patient files shows that most experienced various audiovestibular symptoms, including vertigo and sensorineural hearing loss, with specific audiological and vestibular testing revealing common patterns of dysfunction.
  • The findings suggest that early treatment with immunosuppressive therapy can help prevent severe audiovestibular problems, indicating the need for more research to understand the underlying causes and improve patient outcomes.
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Objective: To describe the genetic characteristics and the management of two very rare cases of unilateral multifocal inner ear and internal auditory canal or cerebellopontine angle cochleovestibular schwannomas not being associated to full neurofibromatosis type 2-related schwannomatosis.

Patients: In a 29-year-old man and a 55-year-old woman with single-sided deafness multifocal unilateral cochleovestibular schwannomas were surgically resected, and hearing was rehabilitated with a cochlear implant (CI). Unaffected tissue was analyzed using next generation sequencing of the NF2 gene.

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Objective: To characterize migraine pathophysiology, presentation, and current treatment strategies, specifically in regard to vestibulocochlear manifestations of migraine.

Methods: Narrative review of available literature.

Results: Migraine disorder can be described as a spectrum of otologic manifestations, with vestibular migraine now recognized with fully-fledged diagnostic criteria.

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Article Synopsis
  • The study aimed to identify otologic symptoms in COVID-19 patients and understand their characteristics during the pandemic.
  • It involved 2,247 participants, revealing that nearly half experienced symptoms such as vertigo, tinnitus, and hearing loss, with variations in prevalence based on gender, age, and occupation.
  • The findings indicate that otologic symptoms are common in those infected with COVID-19 but often recover on their own, highlighting the need for awareness of cochleovestibular and facial nerve involvement in treatment.
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