Scanning Electron Microscopy (SEM) assessment of the T and B lymphocytic sub-population shows alterations in cell immunity in the thyroid gland pathology. The mean per cent figure in 10 normal individuals was 68.8 for T lymphocytes (variation range: 50-83%) and 19.6 for B lymphocytes (variation range: 11-26%); in 12 untreated cases of Graves's disease the mean figure was 78.08% for T and 16.25% for B lymphocytes. The 15 patients with untreated thyroiditis showed a mean of 83.43% for T and 12.78% for B lymphocytes. The increased number of T lymphocytes is a proof of cell immunity alteration.
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Pharmaceutics
December 2024
Department of Hospital Surgery, Department of Plastic and Reconstructive Surgery, Cosmetology and Cell Technology, Pirogov Russian National Research Medical University (RNRMU), 117997 Moscow, Russia.
Background/objectives: The aim was to study the possibilities of biomedical application of gadolinium oxide nanoparticles (GdO NPs) synthesized under industrial conditions, and evaluate their physicochemical properties, redox activity, biological activity, and safety using different human cell lines.
Methods: The powder of GdO NPs was obtained by a process of thermal decomposition of gadolinium carbonate precipitated from nitrate solution, and was studied using transmission electron microscopy (TEM), X-ray diffraction (XRD), Raman spectroscopy, mass spectrometry, and scanning electron microscopy (SEM) with energy dispersive X-ray analyzer (EDX). The redox activity of different concentrations of GdO NPs was studied by the optical spectroscopy (OS) method in the photochemical degradation process of methylene blue dye upon irradiation with an optical source.
Pharmaceutics
December 2024
Department of Pharmacology, and Toxicology, and Biochemistry, Faculty of Pharmacy, Future University in Egypt, Cairo 11865, Egypt.
Skin wrinkles result from a myriad of multifaceted processes involving intrinsic and extrinsic aging. To combat this effect, plant stem cells offer a renewable and eco-friendly source for various industries, including cosmeceuticals. (SM), which contains the bioactive compound Rosmarinic acid (RA) and has been proposed for its anti-wrinkle effect.
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December 2024
i3N and Department of Physics, University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal.
Background/objectives: The unique properties of iron oxide nanoparticles have attracted significant interest within the biomedical community, particularly for magnetic hyperthermia applications. Various synthesis methods have been developed to optimize these nanoparticles.
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Pharmaceutics
December 2024
Unit Operations Lab, School of Technology, Pontifical Catholic University of Rio Grande do Sul, Av. Ipiranga 6681-Prédio 30, Bloco F, Sala 208, Porto Alegre 90619-900, Brazil.
Degradation by physical and chemical agents affects the properties of essential oils; therefore, this study aimed to protect the volatile compounds present in essential oils through biopolymer encapsulation. The (Lam) DC. essential oil was obtained by steam distillation at 2.
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December 2024
College of Pharmacy, Xinjiang Second Medical College, Karamay 834000, China.
, an active component of Arnebia euchroma (Royle) Johnst., has remarkable pharmacological effects, particularly in its anti-tumour activity. Nonetheless, the specific targets and mechanisms of action remain to be further explored.
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