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Bcl-2 and galectin-3 expression is associated with recurrence of ameloblastoma.
Dent Res J (Isfahan)
December 2024
Department of Restorative Dentistry, College of Dentistry, Qazvin University of Medical Sciences, Qazvin, Iran.
Background: Ameloblastoma is a benign odontogenic neoplasm with a high recurrence rate. Identifying cellular and molecular changes in this neoplasm may help predict the recurrence risk. Bcl-2 and galectin-3 are anti-apoptotic proteins associated with the prognosis of many neoplasms.
View Article and Find Full Text PDFFrom Pathogenesis to Precision Medicine: Transformative Advances in Research and Treatment of Ameloblastoma.
Cancer Lett
January 2025
Department of Oral and Maxillofacial & Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Center for Stomatology, National Clinical Research Center for Oral diseases, Shanghai Key Laboratory of Stomatology, Shanghai, China. Electronic address:
Odontogenic neoplasms of the jaw are dominated by ameloblastoma (AM), a locally aggressive epithelial tumor with a significant propensity for recurrence. The World Health Organization's 2022 update to the AMclassification system underscores recent progress in comprehending its underlying mechanisms and refining clinical approaches. Contemporary research has yielded significant insights into the genetic underpinnings of AM, paving the way for the development of precision-based treatment strategies.
View Article and Find Full Text PDFGene expression and immunohistochemistry analysis of ADAMTS-1 and its substrates in odontogenic keratocyst.
Diagn Pathol
January 2025
Cell Culture Laboratory, School of Dentistry, Federal University of Para, Rua Augusto Correa, 01 Guama, Belem, PA, 66075110, Brazil.
Background: Considering the significant participation of the microenvironment in the local aggressiveness of odontogenic keratocysts, this study aims to evaluate the expression of ADAMTS-1 and its substrates, versican, aggrecan and brevican in this locally invasive odontogenic cyst.
Methods: Immunohistochemistry and polymerase chain reaction (PCR) were conducted on 30 cases of odontogenic keratocysts (OKCs) and 20 dental follicles (DFs).
Results: The immunohistochemical expression of these proteins was predominantly cytoplasmic and granular across all samples.
Giant odontoma: A systematic scoping review and case report.
Int J Surg Case Rep
January 2025
Department of Oral and Maxillofacial Surgery, School of Dentistry, Azad University of Medical Sciences, Shiraz, Iran.
Introduction And Importance: The most common type of odontogenic tumor is odontoma. Cases with at least one dimension (sagittal, axial, or coronal) ≥30 mm were categorized as giant odontomas. This study aimed to provide a scoping review of giant odontoma and present a case report.
View Article and Find Full Text PDF[Lacrimal duct obstruction caused by maxillary odontogenic cyst invading lacrimal fossa: a case report].
Zhonghua Kou Qiang Yi Xue Za Zhi
January 2025
Department of Otolaryngology, The Affiliated Yantai Stomatological Hospital, Binzhou Medical University, Yantai264000, China.
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