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Evaluation of MRX PT DOAC as a new screening method for detecting interferences in thrombophilia analyses.
Scand J Clin Lab Invest
January 2025
Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Background: Direct oral anticoagulants (DOACs) can interfere with coagulation analyses, causing erroneous results such as false-positive lupus anticoagulant and false-normal antithrombin, threatening patient safety when overlooked. A test using a prothrombin time quotient method to detect DOAC presence in plasma samples is now commercially available, the MRX PT DOAC, with the result expressed as Clot Time Ratio (CTR).
Objectives: Evaluate the ability of MRX PT DOAC to identify interfering apixaban or rivaroxaban concentrations, identify non-interfering or interfering patient samples, and detect whether a patient is on DOAC treatment.
The Management of the Aortic Arch in Type A Aortic Dissection: Replace, Repair with the AMDS, or Leave for Another Day?
J Cardiovasc Dev Dis
January 2025
Division of Cardiac Surgery, Department of Surgery, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Objectives: Acute type A aortic dissection (ATAAD) is a life-threatening condition that requires emergent surgical intervention. Numerous surgical approaches exist for ATAAD, and controversy remains regarding the optimal arch interventions for ATAAD patients. Aortic Arch Interventions: Approaches to ATAAD repair include hemiarch repair or extended arch repairs, including the hemiarch with a hybrid stent implantation, such as the AMDS hybrid Prosthesis, total arch replacement (TAR), and the use of an elephant trunk and frozen elephant trunk.
View Article and Find Full Text PDFClinical Characteristics and Mortality-Associated Factors in Trauma Patients Undergoing Permanent Versus Temporary Tracheostomy.
Clin Pract
January 2025
Department of Otolaryngology, Faculty of Medicine, Majmaah University, Al-Majmaah 11952, Saudi Arabia.
This study evaluated the characteristics, outcomes, and mortality-associated factors in patients who underwent tracheostomy after traumatic injury to optimize clinical decision-making and patient care in critical trauma settings. A retrospective cohort analysis was conducted using the National Trauma Data Bank (NTDB) records from 2013 to 2016. This study included 41,630 adult trauma patients who underwent tracheostomy procedures.
View Article and Find Full Text PDFClear Aligner Treatment: Indications, Advantages, and Adverse Effects-A Systematic Review.
Dent J (Basel)
January 2025
Section of Orthodontics, Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.
: Clear aligner treatment (CAT) has gained interest among clinicians as well as among patients. The aim of the present study was to systematically review the literature regarding current viewpoints on indications, contraindications, advantages, disadvantages, and adverse effects in CAT. : A search was performed in the PubMed and Embase databases, yielding 18 studies eligible for inclusion.
View Article and Find Full Text PDFKnowledge, Practices, and Attitudes Towards Silver Diamine Fluoride Therapy Among Dentists and Students in Southeastern Spain.
Dent J (Basel)
January 2025
Department of Integrated Pediatric Dentistry, Faculty of Medicine-Dentistry, University of Murcia (Spain), Hospital Morales Meseguer, 2a Planta, C/Marqués de los Vélez, s/n, 30007 Murcia, Spain.
The use of silver diamine fluoride (SDF) has increased in recent years for the management of caries lesions in children and adults. The aim of this study is to determine the level of knowledge and the attitude of Spanish dentists (GDPs) and final-year dental students (DSs) regarding the use of SDF. A cross-sectional survey (questionnaire) was carried out aimed at final-year dental students (DSs) (n = 43) and registered dentists (GDPs) (n = 1050) in the autonomous community of the region of Murcia (Spain).
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