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Saliva Diagnostics in Spaceflight Virology Studies-A Review.
Viruses
December 2024
JES Tech, Human Health and Performance Directorate, Houston, TX 77058, USA.
Many biological markers of normal and disease states can be detected in saliva. The benefits of saliva collection for research include being non-invasive, ease of frequent sample collection, saving time, and being cost-effective. A small volume (≈1 mL) of saliva is enough for these analyses that can be collected in just a few minutes.
View Article and Find Full Text PDFImplementation of Principal Component Analysis (PCA)/Singular Value Decomposition (SVD) and Neural Networks in Constructing a Reduced-Order Model for Virtual Sensing of Mechanical Stress.
Sensors (Basel)
December 2024
Fundación Centro Tecnológico CTC-Scientific and Technological Park of Cantabria (PCTCAN), Street Isabel Torres Nº 1, 39011 Santander, Spain.
This study presents the design and validation of a numerical method based on an AI-driven ROM framework for implementing stress virtual sensing. By leveraging Reduced-Order Models (ROMs), the research aims to develop a virtual stress transducer capable of the real-time monitoring of mechanical stresses in mechanical components previously analyzed with high-resolution FEM simulations under a wide range of multiple load scenarios. The ROM is constructed through neural networks trained on Finite Element Method (FEM) outputs from multiple scenarios, resulting in a simplified yet highly accurate model that can be easily implemented digitally.
View Article and Find Full Text PDFSensitivity Analysis of an Optical Interferometric Surface Stress Ethanol Gas Sensor with a Freestanding Nanosheet.
Sensors (Basel)
December 2024
Department of Electrical and Electronic Information Engineering, Toyohashi University of Technology, Toyohashi 441-8580, Japan.
Ethanol (EtOH) gas detection has garnered considerable attention owing to its wide range of applications in industries such as food, pharmaceuticals, medical diagnostics, and fuel management. The development of highly sensitive EtOH-gas sensors has become a focus of research. This study proposes an optical interferometric surface stress sensor for detecting EtOH gas.
View Article and Find Full Text PDFResearch on the Stress Characteristics of Reuse of Semi-Rigid Base.
Sensors (Basel)
December 2024
School of Highway, Chang'an University, Middle Section of South Erhuan Road, Xi'an 710064, China.
Semi-rigid bases are widely used in road construction due to their excellent properties, high rigidity, and frost resistance, and they have been in service for many years. However, as the service life increases, the maintenance demands also grow, with traditional maintenance methods still being the primary approach. Based on a typical case using ground-penetrating radar (GPR) technology, this study explores the issue of cracks in semi-rigid bases and their impact on overlay layers.
View Article and Find Full Text PDFOral Delivery of miR146a Conjugated to Cerium Oxide Nanoparticles Improves an Established T Cell-Mediated Experimental Colitis in Mice.
Pharmaceutics
December 2024
Laboratory for Fetal and Regenerative Biology, Department of Surgery, University of Arizona Tucson College of Medicine, Banner Children's at Diamond Children's Medical Center, 1656 E Mabel St, Rm 230, Tucson, AZ 85721, USA.
Dysregulated inflammation and oxidative stress are strongly implicated in the pathogenesis of inflammatory bowel disease. We have developed a novel therapeutic that targets inflammation and oxidative stress. It is comprised of microRNA-146a (miR146a)-loaded cerium oxide nanoparticles (CNPs) (CNP-miR146a).
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