AI Article Synopsis
- A study was conducted on vaginal smears from three groups of menopausal women over 50 years old: 597 healthy controls, 134 with squamous cervical cancer, and 167 with endometrial adenocarcinoma.
- The study found that 4% of healthy women showed estrogenic effects, compared to 6% in cervical cancer patients and 12% in endometrial cancer patients.
- The results suggest that increased estrogenic activity in women more than one year post-menopause should prompt further clinical evaluation to rule out possible asymptomatic cancers of the cervix or endometrium.
Article Abstract
Cytohormonal evaluation was made on vaginal smears of three groups of women, all over 50 years of age and menopausal for at least one year. The first group consisted of 597 control healthy women, and the second and the third groups consisted of 134 patients with squamous cervical cancer and 167 patients with endometrial adenocarcinoma, respectively. It was found that 4% of the 597 healthy women had vaginal smears with an unequivocal estrogenic effect as compared with a 6% incidence in patients with squamous carcinoma of the cervix and a 12% incidence in patients with endometrial adenocarcinoma. It is concluded that increased estrogenic activity in a woman more than one year after menopause should lead to a thorough clinical investigation to exclude an asymptomatic carcinoma of the cervix or endometrium.
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