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Lifei Qingchang Tang attenuates acute lung injury the NF-κB and MAPK signaling pathways.
J Asian Nat Prod Res
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The First Affiliated Hospital of Guangzhou Medical University, Guangzhou510120, China.
Acute lung injury (ALI) has high morbidity and mortality. Lifei Qingchang Tang (LFQCT), a traditional Chinese medicine, has antioxidant and anti-inflammatory properties but its mechanism in ALI remains unclear. , LFQCT reduced intracellular Ca, ROS, and NO in LPS-induced RAW 264.
View Article and Find Full Text PDFOne Month of Brief Weekly Magnetic Field Therapy Enhances the Anticancer Potential of Female Human Sera: Randomized Double-Blind Pilot Study.
Cells
February 2025
Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.
Preclinical studies have shown that the blood from female mice exposed weekly to magnetic fields inhibited breast cancer growth. This double-blind randomized controlled trial investigated whether analogous magnetic therapy could produce similar anticancer sera from human subjects. Twenty-six healthy adult females (ages 30-45) were assigned to either a magnetic therapy group, receiving twice weekly 1 mT magnetic exposures (10 min/session) for 4 weeks, or a control group, who underwent identical sham exposure.
View Article and Find Full Text PDFCurcumin-loaded Pickering emulsions stabilized by Spanish mackerel protein-pectin for ameliorating ulcerative colitis through barrier repair and anti-inflammatory effects.
Int J Biol Macromol
March 2025
State Key Laboratory of Marine Food Processing and Safety Control, Dalian Polytechnic University, Dalian 116034, Liaoning, China; Academy of Food Interdisciplinary Science, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, Liaoning, China; National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian 116034, Liaoning, China; Collaborative Innovation Center of Seafood Deep Processing, Dalian Polytechnic University, Dalian 116034, Liaoning, China; Dalian Key Laboratory for Precision Nutrition, Dalian Polytechnic University, Dalian 116034, Liaoning, China. Electronic address:
Curcumin (Cur) has gained considerable recognition because of its anti-inflammatory and antioxidant effects as a bioactive compound, but its water insolubility and low bioaccessibility limit its application in food industry. In this study, Pickering emulsion stabilized by Spanish mackerel protein and pectin complex (SMP/PEC) was prepared to deliver curcumin, and its alleviating effects on DSS-induced ulcerative colitis (UC) were investigated. The emulsions stabilized by SMP/PEC 1:1 inhibited phase separation, had good rheological properties and the emulsions were stable at high temperatures, centrifugation, salt ions, and pH conditions.
View Article and Find Full Text PDFDental Restorative Viability of Zinc Oxide Nanoparticle-Reinforced Zirconia and Baghdadite Ceramic Composites.
J Biomed Mater Res B Appl Biomater
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Department of Mining, Metallurgical and Materials Engineering, College of Engineering, University of the Philippines Diliman, Quezon City, Philippines.
This study explores the enhancement of properties in zirconia-based ceramic dental restorative materials through the incorporation of baghdadite (CaZrSiO) and zinc oxide (ZnO) nanoparticles. Baghdadite was synthesized via a solid-state sintering method and integrated into zirconia to form baghdadite/zirconia ceramic composites. These composites were sintered with varying concentrations of baghdadite (0%, 5%, and 10%) to enhance bioactivity and support bone tissue repair, and incorporated with 0.
View Article and Find Full Text PDFDesign and development of a novel multi-epitope DNA vaccine candidate against infectious bronchitis virus: an immunoinformatic approach.
Arch Microbiol
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Tianjin Key Laboratory of Agricultural Animal Breeding and Healthy Husbandry, College of Animal Science and Veterinary Medicine, Tianjin Agricultural University, No. 22, Jinjing Road, Xiqing District, Tianjin, 300392, People's Republic of China.
Avian infectious bronchitis (IB) is one of the major respiratory diseases in poultry. At present, attenuated vaccines are the main commercial vaccines, but they have many defects. We aimed to construct a novel multi-epitope DNA vaccine based on avian infectious bronchitis virus (IBV) S1 and N proteins for the prevention of IBV infection.
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