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Bench Surgery with Robot-assisted Kidney Autotransplantation for Complex Kidney Tumors: Technique and Outcomes from a Single Center.
Eur Urol Open Sci
April 2025
Department of Urology, the Third Medical Center, Chinese PLA General Hospital, Beijing, People's Republic of China.
Background And Objective: Bench surgery (BenS) with kidney autotransplantation serves as an alternative to nephron-sparing surgery (NSS) for patients harboring high-complexity renal tumors that are ineligible for in situ partial nephrectomy (PN). However, the experience of BenS with robot-assisted kidney autotransplantation (RAKAT) has been scarce in such cases. Here, we describe the operative techniques, and functional and oncological outcomes of BenS with RAKAT.
View Article and Find Full Text PDFBDNF-mediated depressor response by direct baroreceptor activation benefits for prevention and control of hypertension in high-latitude cold region.
Neuropeptides
February 2025
Department of Pharmacy, Tianjin Cancer Hospital Airport Hospital, National Clinical Research Center for Cancer, Tianjin 300308, China. Electronic address:
Brian-derived neurotrophic factor (BDNF)-tyrosine kinase B (TrkB) signaling impacts on neuronal and cardiovascular physiology; however, its role in neurocontrol of circulation via baroreflex afferent pathway is largely unknown. Gene and protein expression of BDNF/TrkB were detected in the nodose (NG) and nucleus of tractus solitary (NTS) and expression levels were higher in male compared with female rats, which is relevant well with the blood pressure (BP, males > females in average). Microinjection of BDNF into NG dose-dependently reduced BP and this reduction was more dramatic in shamed control vs.
View Article and Find Full Text PDFHigh density probes reveal medullary seizure and rapid medullary shutdown in a model of fatal apnea in seizure.
bioRxiv
February 2025
Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Objective: Sudden unexpected death in epilepsy (SUDEP) is suggested to be a cardiorespiratory collapse that occurs shortly after a seizure. Prior work in rats suggests that reflexive apneas (produced by stimulation of trigeminal or vagal peripheral sensory targets) is highly fatal during seizure but well tolerated otherwise. These reflexes share network connectivity in the medulla, particularly the caudal solitary nucleus (NTS) and ventral respiratory column (VRC), and possibly other intermediate structures.
View Article and Find Full Text PDFBenign Solitary Nerve Sheath Tumors: A Single Center Retrospective Case Series.
J Voice
February 2025
Department of ENT, Christian Medical College, Vellore, Tamil Nadu, India. Electronic address:
Aim: To review the epidemiology, presentation, and outcomes of benign laryngeal nerve sheath tumors treated at our center.
Methods: We retrospectively analyzed the demographic data (age and sex), clinical profile, imaging, management, and follow-up of histopathologically confirmed benign solitary nerve sheath tumors of the larynx from January 2016 to August 2023.
Results: There were a total of 10 cases, 80% were schwannomas, and 20% were neurofibromas, all being sporadic with none associated with neurofibromatosis or schwannomatosis.
The genome of the solitary bee Tetrapedia diversipes (Hymenoptera, Apidae).
G3 (Bethesda)
February 2025
Departamento de Genética e Biologia Evolutiva, Instituto de Biociências, Universidade de São Paulo, Rua do Matão, 277, CEP 05508-090, São Paulo, SP, Brazil.
Tetrapedia diversipes is a Neotropical solitary bee commonly found in trap-nests, known for its morphological adaptations for floral oil collection and prepupal diapause during the cold and dry season. Here, we present the genome assembly of T. diversipes (332 Mbp), comprising 2,575 scaffolds, with 15,028 predicted protein-coding genes.
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