AI Article Synopsis
- The study investigated the presence and activity of dehydrogenases and diaphorases in the carotid body and superior cervical ganglion of rats using histochemical and cytophotometric methods.
- The research found an increase in NAD--diaphorase activities in the interlobe tissue of the carotid body when rats were exposed to low oxygen and high carbon dioxide levels, while similar changes were not observed in the superior cervical ganglion.
- These enzyme activity changes in the carotid body are believed to relate to its role as a chemoreceptor, particularly in relation to specific cells involved in sensing environmental changes.
Article Abstract
The distribution and relative activities of some dehydrogenases and diaphorases in the rat's carotid body and ganglion cervicale superior were studied histochemically and cytophotometrically. The treatment of rats by the medium with decreased oxygen and increased carbon dioxide contents, a reliable rise of NAD--diaphorase activities was found in the interlobe tissue and (less expressed and late appearing) in the principal cells. In contrast, such changes were not observed in the ganglion cervicale superioir, that have not a special chemoreceptory function. It is supposed that these changes in enzyme activities in the carotid body is due to the chemoreceptory function of the intralobe tissue containing the IInd type cells and "special" cells of sensitive nerve terminals.
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